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Volume - 63 , Issue 02
28 Feb 2023

Azerbaijan Medical Journal

(ISSN: 0005-2523)

Azerbaijan medical journal (ISSN: 0005-2523) - is a scopus indexed journal since 1961. The publisher of the journal is Izdatel'stvo Elm by WHO Office in Azerbaijan. Azerbaijan medical journal (AMJ) is also UGC approved. The journal publishes general medicine, health science, psychological, pharmaceutical journals and so on. Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Interventional Pulmonology Zhenkong Kexue yu Jishu Xuebao/Journal of Vacuum Science and Technology

Aim and Scope

Azerbaijan Medical Journal

Azerbaijan Medical Journal (ISSN: 0005-2523) - is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to. Zhongguo Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of China University of Petroleum (Edition of Natural Science) Tobacco Science and Technology Teikyo Medical Journal Connected Health Wuhan Ligong Daxue Xuebao (Jiaotong Kexue Yu Gongcheng Ban)/Journal of Wuhan University of Technology (Transportation Science and Engineering) Zhonghua yi shi za zhi (Beijing, China : 1980) Agricultural Mechanization in Asia, Africa and Latin America International Medical Journal Technology Reports of Kansai University Asia Life Sciences Open Access Journals Tagliche Praxis

Anatomy Physiology Biochemistry Pharmacology Pathology Forensic medicine Microbiology Community Medicine Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases Anaesthesia Cancer research Neurosurgery Orthopedics Gastroenterology Neurology Nephrology Medical education Orthopaedics Paediatrics Reproduction Cardiology Diabetes Surgery Nursing Otolaryngology Dental Psychology Anesthesiology Dermatology Endocrinology Hepatology Urology Venereology Psychiatry Biotechnology Pharmacy ENT Pharmaceutical Chemistry Pharmaceutical Analysis Pharmaceutics Pulmonology Pharmacognosy Pharmaceutical Phatmaceutical Technology Biopharmaceutics Pharmacokinetics Pharmacodynamics Industrial Pharmacy Drug Design Quality Assurance Drug Regulatory Affairs Phytochemistry Drug Delivery Systems Pharmaceutical Nanotechnology Pharmaceutical Microbiology Hospital Pharmacy Clinical Pharmacy Pharmacy Practice Drug Discovery Drug Metabolism Toxicology Clinical Research Pharmacogenomics Phrmacoinformatics Pharmacovigilance< Life Sciences like Chemistry Biomedical Sciences Microbiology Immunology Forensic Epidemiology Oncology Biomedicine Dentistry Physiotherapy Gynaecology Dermatoepidemiology Neuroscience Ophthalmology Sexology Osteology Kinesiology Angiology/Vascular Medicine Critical care Medicine Haematology Infectious Diseases and Vaccinology Bariatrics Pharmacy and Nursing Pharmacognosy and Phytochemistry Radiobiology Clinical immunology Clinical and Hospital Pharmacy Cell Biology Genomics and Proteomics Healthcare Services Healthcare Management Bioinformatics and Biotechnology Geriatric Medicine Bulletin of National Institute of Health Sciences Journal of the Austrian Society of Agricultural Economics Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Interventional Pulmonology Zhenkong Kexue yu Jishu Xuebao/Journal of Vacuum Science and Technology Wuhan Ligong Daxue Xuebao (Jiaotong Kexue Yu Gongcheng Ban)/Journal of Wuhan University of Technology (Transportation Science and Engineering) Zhonghua yi shi za zhi (Beijing, China : 1980) Zhongguo Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of China University of Petroleum (Edition of Natural Science) Tobacco Science and Technology Teikyo Medical Journal Connected Health

Latest Journals Agricultural Mechanization in Asia, Africa and Latin America International Medical Journal Technology Reports of Kansai University Asia Life Sciences Open Access Journals Tagliche Praxis Bulletin of National Institute of Health Sciences Journal of the Austrian Society of Agricultural Economics

Azerbaijan Medical Journal

Analysis of Household and Environmental Determinants with Stunting Incidents in Ambon Bay, Ambon City
Journal ID : AMJ-28-01-2023-11158; Author : Khasrul Tsani Waliulu, Ridwan Amiruddin, Andi Zulkifli,
Abstract : The prevalence of stunting in Indonesia 2020 is 31.8%, in 2021 the prevalence province of Maluku stunting under five is 28.7%, and the prevalence stunting in Ambon city 21.8%. the aim of the study was to determinants household factors and environmental factors on the incidence stunting. The research was conducted in Teluk Ambon sub-district, Ambon City. Research is design case control study. Total sample was 228 toddlers aged 24-59 months, consisting of 114 stunting cases and 114 not respondents stunted. Sampling was done by systematic random sampling. Data were analyzed using Chi-Square test and Multiple Logistic Regression. Results of Chi-Square test on the ANC quality variable Mother p=0.001 OR (4.5), KEK p=0.015 OR (1.9), parenting style p=0.041 OR (1.7), Exclusive breastfeeding p=0.000 OR (3.8),children anemia p=0.004 OR (3.3),diarrhea and/or ISPA p=0.000 OR (4.3),smoking in house p=0.000 OR (4.4), education p=0.005 OR (2.4), income p=0.000 OR (3.7), water quality p=0.027 OR (2.0), and basic sanitation p=0.001 OR (2.5) 11 variables show there influence on incidence of stunting and are a risk factor stunting events. Where as immunization history p=0.056 and monitoring of growth development p=0.196 had no effect the incidence of stunting. Test Multiple Logistic Regressionon household determinants the most dominant variable is the quality ANC Mother (OR 3.6 95% CI 1.29 – 10.2) after being controlled. The most dominant environmental determinant is basic sanitation (OR 2.5 95% CI 1.48 – 4.31). For household and environmental determinants, the most dominant variable ANC quality Mother (OR 3.6 95% CI 1.29 – 10.2) after being controlled.
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PRIMARY TUBERCULOSIS OF CERVIX MIMICKING CERVICAL CARCINOMA : A RARE CASE REPORT
Journal ID : AMJ-27-01-2023-11156; Author : Nugraha Utama Pelupessy, Rina Previana, Andi Siiti Halija Diawanti,
Abstract : Primary tuberculosis of the cervix is a very rare case and its prevalence is only about 0.1-0.65 % of all tuberculosis cases. Lesions in cervical tuberculosis can resemble lesions in cervical carcinoma with similar complaints such as foul-smelling vaginal discharge, abnormal bleeding, and symptoms of malaise. However, the diagnosis can be made by isolating the acid-fast bacillus on microscopy or histopathology. We report a rare case of primary tuberculosis of the cervix, which was suspected as carcinoma cervix on clinical examination but turned out to be a case of cervical tuberculosis based on the histopathological result. At nine months, the cervix had an almost normal appearance, and complaints from the patient were lessened.
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Intravitreal Resveratrol Prevents Progressivity of Retinal Ganglion Cell Loss after Retinal Ischemic-Reperfusion Injury
Journal ID : AMJ-26-01-2023-11150; Author : Amelia Shinta Prasetya, Evelyn Komaratih, Wimbo Sasono, I Ketut Sudiana, Chrismawan Ardiyanto, Mercia Chrysanti, Maria Debora Niken Larasati, Yulia Primitasari, Nurwasis,
Abstract : Retinal ganglion cells (RGC) are the most commonly affected cell type in optic neuropathies following acute high IOP injury that induced cell death mechanism, such as apoptosis. Resveratrol is a potential antioxidant against various ocular disease, as well as its anti-inflammatory, anti-angiogenic, and anti-apoptotic effects. In this in vivo study, 20 healthy adult male Rattus Norvegicus were separated into 4 groups and given intervention retinal ischemic reperfusion injury (I/R) by increasing intraocular pressure to 110 mmHg for 60 minutes. Resveratrol (RSV) 100μM was injected intravitreally in the IR+RSV group thus enucleated in 7th day. Enucleated eye were immunohistochemically examined for Bax and Caspase-3 expression. Bax and Caspase-3 level was significantly increased between control group and treatment group (IR7+PBS, IR7+RSV) (P <0.01 and P<0.05); and between intervention group IR0 and IR7+PBS (P<0.01). There was also significant decrease between IR7+PBS and IR7+RSV (P<0.05). This study concluded that Resveratrol intravitreal helps to prevent progressivity of retinal ganglion cell loss by decreasing Bax and Caspase-3 expression after ischemic reperfusion injury in the animal model.
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Effect of andaliman fruit on the improvement of kidney function and histological structure
Journal ID : AMJ-26-01-2023-11147; Author : Christine Christine, Liena Soegianto, Chrismis Novalinda Ginting, Linda Chiuman,
Abstract : Glomerulonephritis is a disease of inflammation on kidney’s glomerulus that is marked by the damage of glomerular capillary wall, increase of membrane permeability, and decrease of glomerular filtration rate. Glomerulonephritis needs to be detected and treated early to minimize kidney damage. Chronic glomerulonephritis can slowly be progressive and periodically cause the loss of kidney function. Oxidative stress and inflammation is known to have a role in the pathogenesis of Acute Glomerulonephritis. Andaliman fruit (Zanthoxylum acanthopodium DC) is known to have plenty of benefits, namely as antioxidant and anti-inflammation. To determine the effect of andaliman fruit ethanol extract towards measurement of creatine, urea, and kidney histologic structure on mice models with acute glomerulonephritis. Research design is an experimental study using the pretest posttest with control group design method on Streptokinase induced acute glomerulonephritis Rattus norvegicus rat model. This study compares the effect of andaliman fruit ethanol extract on control group and treatment group receiving each the dose of 100 mg/kg/day, 200 mg/kg/day and 300 mg/kg/day. There was a significant difference (p<0.05) creatinine and urea level between groups after given the andaliman fruit ethanol extract on acute glomerulonephritis rat model after 14 days. The most effective change on kidney histologic structure could be seen in a group receiving the dose of 100 mg/kg/day. This study showed the anti-inflammatory activity of andaliman fruit (Zanthoxylum acanthopodium DC) that could be seen from the improvement of kidney function and histologic structure.
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Study of oxidative stress and antioxidant levels in Emphysema patients
Journal ID : AMJ-25-01-2023-11138; Author : Dr Shaik Sajeed, Dr Nagaraj, Dr Anand K. Pyati, Dr Mirza Sharif Ahmed Baig,
Abstract : Emphysema is associated with high incidence of morbidity and mortality in india. The imbalance between oxidative stress and antioxidants play a major role in the Emphysema pathogenesis. Aim of this study is to estimate serum levels of Malondialdehyde (MDA) as a biomarker of lipid peroxidation and non enzymatic antioxidant vitamin E in Emphysema patients and healthy controls. A total number of 80 subjects comprising of 40 healthy controls and 40 Emphysema cases were studied. Serum malondialdehyde estimated by Kei Satoh Method and Serum vitamin E was measured by Baker and Frank method. Serum MDA was significantly increased in Emphysema patients when compared to controls where as serum level of vitamin E significantly decreased in Emphysema patients when compared to controls. Oxidative stress is increased in Emphysema patients which seems to be associated with active smoking habit and also due to systemic inflammation. The decrease in level of antioxidant in Emphysema patients appears to be consequence of increased oxidative stress and its excess consumption. By advising rich antioxidant diet or additional supplementation of antioxidants may prevent the further oxidative damage in emphysema patients.
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Human Metabolomics in patients with inflammatory bowel disease
Journal ID : AMJ-24-01-2023-11134; Author : Nikolay Tsonev, Dimitar Zvezdov,
Abstract : Inflammatory bowel diseases comprise of ulcerative colitis and Crohn's disease, both of which have increasing incidence. Despite not having completely undestood pathogenesis, genetic factors, environmental factors and microbiota are thought to play a role in a predisposed individual. Common symptoms include abdominal pain, diarrhea, fever, weight loss and rectal bleeding. Diagnosis is made by clinical, laboratory, endoscopic, radiologic and histologic examinations. Nevertheless, about 15% of patients do not have a definitive diagnosis. Metabolomics measures metabolites in a biological sample (feces, serum, urine, tissue and air) thereby having the potential to clarify disease pathogenesis and find new biomarkers, which will then aid in diagnosis, guide therapy and give prognosis.
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Management of antithrombotics in gastrointestinal endoscopy
Journal ID : AMJ-24-01-2023-11133; Author : Nikolay Tsonev, Diana Vandeva, Katerina Toncheva,
Abstract : Anticoagulants and antiplatelet agents are widely used drugs for cardiovascular prevention and reducing the risk of thromboembolic events. Gastrointestinal bleeding represents a serious complication of their use. On the other hand gastrointestinal endoscopy is related with bleeding risk – there is bleeding risk stratification according to endoscopic procedures (high and low risk ones). Treatment with antithrombotic drugs in periprocedural endoscopic period is based on balancing the bleeding risk against the thromboembolic risk. Antithrombotic agents in endoscopic procedures with lower bleeding risk are not needed to be withheld. It’s recommended temporary discontinuation of antithrombotic treatment in high risk endoscopic procedures and to consider use of “bridging” therapy with LWMH for patients on vitamin K antagonist who are at high thrombotic risk. Evaluating cardiovascular risk and management of antithrombotic therapy could be a challenge for gastrointestinal endoscopist, therefore collaboration with cardiologist is of great importance, at least for some patients.
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Comparison of Retention Between Two Aligner Products Before and After Thermocycling
Journal ID : AMJ-24-01-2023-11132; Author : Ezzuldin Yaseen Aljumaily, Ali R. Al-Khatib,
Abstract : The use of clear orthodontic aligners has increased as an alternative to conventional braces. Therefore, knowledge about the characteristics of the aligner materials can help to provide more accurate treatment results and give orthodontists who are utilizing or planning to employ this technology more information about their behaviour. This study aimed to investigate and compare the effect of thermocycling on the retention measurement of two aligner products used in the fabrication of orthodontic aligners. Two thermoplastic products of Duran® 0.75 mm and Erkodur® 1 mm were used in this study. Digital impressions were obtained for the upper and lower arches of 10 patients. Digital models with two rectangular attachments in the first and second premolars were constructed by using blue sky plan software. After the construction of orthodontic aligners, retention tests were measured using a tensile test with a universal testing machine to measure the maximum forces required to remove the aligners from the models. Twenty aligners were fabricated for each type of product, and measurements were conducted before and after thermocycling. Duran® upper aligners retention showed no significant changes in comparison with Erkodur®, however, Duran® lower aligners showed significant changes in comparison with Erkodur® before thermocycling. However, Duran® aligners showed no significant change, whereas, Erkodur® in both upper and lower arches showed a significant decrease in retention after thermocycling. The retention of the Duran® aligner is higher than that of Erkodur® and thermocycling decreased the retention of the aligners fabricated from Erkodur® in comparison with Duran® aligners.
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Correlation Between Total Nasal Symptom Score and Epworth Sleepiness Scale in Allergic Rhinitis Patients
Journal ID : AMJ-24-01-2023-11127; Author : Yohanes Dimas Pamungkas Priyambodo, Dwi Reno Pawarti, Nyilo Purnami,
Abstract : Symptoms of allergic rhinitis (AR) in the form of sneezing, runny nose, stuffy nose, and itchy nose which are chronic, progressive, irreversible in advanced stages can cause sleep disturbances. Allergic rhinitis can be assessed subjectively by assessing the symptoms that appear using the Total Nasal Symptom Score. Sleep disturbance can be assessed subjectively by analyzing the level of daytime fatigue using the Epworth Sleepiness Scale questionnaire. This study aims to find the relationship between the Total Nasal Symptom Score and the Epworth Sleepiness Scale in allergic rhinitis patients. This type of research is analytic observational with a cross sectional study design. The research sample was AR patients who had been treated at URJ ENT-BKL RSUD Dr. Soetomo Surabaya in the period 1 January 2019-31 December 2021 (n=115). Baseline data, TNSS, and ESS were obtained using a google form questionnaire. The collected data was filtered using exclusion criteria and then statistically analyzed using the Spearman correlation test. The two patients with normal TNSS were all known to have normal ESS. Fifty-two patients with mild TNSS were all found to have normal ESS. Forty-two patients with moderate TNSS were found to have normal ESS values of 47.62%, mild ESS of 23.81%, moderate ESS of 28.57%, and no severe ESS. Nineteen patients with severe TNSS did not have normal ESS, while 15.79% of mild ESS had mild ESS, 26.32% moderate ESS and 57.89% severe ESS. The Spearman correlation test results from the research data showed a significant relationship (p = 0.000), with a positive correlation and a strong correlation level (r = 0.785). There is a strong positive relationship between TNSS and ESS in AR patients.
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Multimodal Imaging Diagnosis of Hemophilic Knee Arthropathy: A Case Series
Journal ID : AMJ-23-01-2023-11118; Author : Marisa Citra Kinasih, Hermina Sukmaningtyas, Miftakhul Jannah,
Abstract : Hemophilia is a congenital disease resulting from a severe coagulation factor VIII or factor IX deficiency. This condition causes the emergence of target joints, which in 30% of hemophilic patients develops hemophilic arthropathy. We reported three cases of hemophilic arthropathy that were examined using conventional radiology modalities, ultrasound and 1.5T MRI at Dr. Kariadi Semarang. Conventional radiological examinations were assessed using the Arnold Hiltgartner qualitative scale and the Petterson quantitative score. The first case was an 11 years old child with type B hemophilia, and right knee pain with an Arnold Hiltgartner scale of 4 and a Petterson score of 7. An MRI examination obtained an IPSG MRI score of 7. The second case is an 8 years old child with hemophilia type B who complains of a swollen right knee. On examination, the Arnold Hiltgartner scale was 4, and the Petterson score was 7. The results of the ultrasound examination showed a HEAD-US score of 6. The third case is a 28 years old man with hemophilia type A and right knee pain, with an Arnold Hiltgartner scale of 5 and a Petterson score of 12. In conclusion, conventional radiography is a sensitive initial examination for moderate and severe degrees of hemophilic arthropathy. Ultrasound modality is an effective follow-up examination in assessing soft tissue abnormalities and osteochondral changes, while MRI has the best sensitivity for detecting hemophilic arthropathy.
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