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Volume - 63 , Issue 04
05 Apr 2023

Azerbaijan Medical Journal

(ISSN: 0005-2523)

Azerbaijan medical journal (ISSN: 0005-2523) - is a scopus indexed journal since 1961. The publisher of the journal is Izdatel'stvo Elm by WHO Office in Azerbaijan. Azerbaijan medical journal (AMJ) is also UGC approved. The journal publishes general medicine, health science, psychological, pharmaceutical journals and so on. Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Interventional Pulmonology Zhenkong Kexue yu Jishu Xuebao/Journal of Vacuum Science and Technology

Aim and Scope

Azerbaijan Medical Journal

Azerbaijan Medical Journal (ISSN: 0005-2523) - is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to. Zhongguo Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of China University of Petroleum (Edition of Natural Science) Tobacco Science and Technology Teikyo Medical Journal Connected Health Wuhan Ligong Daxue Xuebao (Jiaotong Kexue Yu Gongcheng Ban)/Journal of Wuhan University of Technology (Transportation Science and Engineering) Zhonghua yi shi za zhi (Beijing, China : 1980) Agricultural Mechanization in Asia, Africa and Latin America International Medical Journal Technology Reports of Kansai University Asia Life Sciences Open Access Journals Tagliche Praxis

Anatomy Physiology Biochemistry Pharmacology Pathology Forensic medicine Microbiology Community Medicine Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases Anaesthesia Cancer research Neurosurgery Orthopedics Gastroenterology Neurology Nephrology Medical education Orthopaedics Paediatrics Reproduction Cardiology Diabetes Surgery Nursing Otolaryngology Dental Psychology Anesthesiology Dermatology Endocrinology Hepatology Urology Venereology Psychiatry Biotechnology Pharmacy ENT Pharmaceutical Chemistry Pharmaceutical Analysis Pharmaceutics Pulmonology Pharmacognosy Pharmaceutical Phatmaceutical Technology Biopharmaceutics Pharmacokinetics Pharmacodynamics Industrial Pharmacy Drug Design Quality Assurance Drug Regulatory Affairs Phytochemistry Drug Delivery Systems Pharmaceutical Nanotechnology Pharmaceutical Microbiology Hospital Pharmacy Clinical Pharmacy Pharmacy Practice Drug Discovery Drug Metabolism Toxicology Clinical Research Pharmacogenomics Phrmacoinformatics Pharmacovigilance< Life Sciences like Chemistry Biomedical Sciences Microbiology Immunology Forensic Epidemiology Oncology Biomedicine Dentistry Physiotherapy Gynaecology Dermatoepidemiology Neuroscience Ophthalmology Sexology Osteology Kinesiology Angiology/Vascular Medicine Critical care Medicine Haematology Infectious Diseases and Vaccinology Bariatrics Pharmacy and Nursing Pharmacognosy and Phytochemistry Radiobiology Clinical immunology Clinical and Hospital Pharmacy Cell Biology Genomics and Proteomics Healthcare Services Healthcare Management Bioinformatics and Biotechnology Geriatric Medicine Bulletin of National Institute of Health Sciences Journal of the Austrian Society of Agricultural Economics Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Interventional Pulmonology Zhenkong Kexue yu Jishu Xuebao/Journal of Vacuum Science and Technology Wuhan Ligong Daxue Xuebao (Jiaotong Kexue Yu Gongcheng Ban)/Journal of Wuhan University of Technology (Transportation Science and Engineering) Zhonghua yi shi za zhi (Beijing, China : 1980) Zhongguo Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of China University of Petroleum (Edition of Natural Science) Tobacco Science and Technology Teikyo Medical Journal Connected Health

Latest Journals

Azerbaijan Medical Journal

Agricultural Mechanization in Asia, Africa and Latin America International Medical Journal Technology Reports of Kansai University Asia Life Sciences Open Access Journals Tagliche Praxis Bulletin of National Institute of Health Sciences Journal of the Austrian Society of Agricultural Economics
THE POTENTIAL ROLE OF ANDROGRAPHIS PANICULATA AGAINST SEPSIS BY INHIBITING NF-KB P65 AND iNOS IN LIPOPOLYSACCHARIDE-INDUCED RAT MODEL
Journal ID : AMJ-03-09-2022-10509; Author : Sumiyati Sumiyati, Yan Wisnu Prajoko, Vega Karlowee, Novan Adi Setyawan, Neni Susilaningsih, Nyoman Suci Widyastiti,
Abstract : Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Andrographis paniculata (AGP) was anti-inflammatory by inhibiting nuclear factor-kappa B (NF-κB), a family of transcription factors that plays a central role in the inducible nitric oxide synthase (iNOS) expression. To prove the effect of AGP on NF-κB p65 and iNOS expression in lipopolysaccharide-induced liver injury in a rat model of sepsis. Immunohistochemistry (IHC) was performed on 30 liver paraffin blocks from 5 groups of male Wistar rats: K1: healthy control; K2: negative control; P1, P2, and P: rats had given AGP doses of 200, 400, and 500 mg/kg BW/day for 14 days. The mean NF-κB p65 and iNOS expression scores in the K1: 3.83±0.408 and 2.83±0.753; K2: 4.00±0.000 and 3.67±0.516; P1: 3.50±0.837 and 3.50±0.837; P2: 3.83±0.408 and 3.83±0.408; P3: 3.83±0.408 and 3.67±0.516. AGP doses of 200, 400, and 500 mg/kg BW/day did not affect NF-κB p65 and iNOS expression in lipopolysaccharide-induced liver injury in a rat model of sepsis. The NF-κB p65 and iNOS expression had a significant correlation (p<0.05) with a coefficient value of 0.514 (moderate). AGP extract prevents the accumulation of lipids that lead to liver necrosis. NF-κB p65 expression had a significant correlation with iNOS expression (p<0.05).
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Compound Heterozygosity of HB Adana and HB Constant Spring: A Case Report
Journal ID : AMJ-03-09-2022-10508; Author : Nyoman Suci Widyastiti, Ita Margaretha Nainggolan, Tri Ratnaningsih, Usi Sukorini,
Abstract : Alpha thalassemia is a genetic disorder of hemoglobin synthesis deletion or non-deletion mutation of the alpha-globin gene. Non-deletional mutations cause abnormalities in the structure of alpha-globin chain, creating an unstable variant of hemoglobin. Furthermore, hemoglobin Adana (HbAdana) and Constant Spring (HbCS) are common non-deletional alpha-thalassemia in Indonesia. However, compound heterozygosity cases of these types of mutations have rarely been reported. A 12-year-old boy is hospitalized with anemia, and complete blood count showed hemoglobin 9.1 g/dL, Mean Corpuscular Volume (MCV) 87.2 fl, and Mean Corpuscular Hemoglobin (MCH) 24.3 pg. On microcapillary hemoglobin electrophoresis examination, HbA 95.7%, HbA2 1.5%, and HbC 2.8% were obtained, and they led to the suspicion of HbCS. Furthermore, examination of polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) found compound heterozygosity of HbAdana and HbCS. The genetic inheritance of compound heterozygosity Hb Adana and HbCS was discovered as the father was heterozygous for HbCS and the mother was heterozygous for Hb Adana. Generally, non-deletional mutations produce variant hemoglobin that is not clinically significant. However, when the point mutation occurs in essential amino acid residues, it will result in very unstable hemoglobin, which causes more serious clinical symptoms of hemolytic anemia than the deletional mutation. HbAdana and HbCS are variants of alpha thalassemia that are very unstable and can easily prevent hemolysis. Therefore, the compound heterozygosity of the two non-deletional mutations causes recurrent severe anemia. The compound heterozygosity of non-deletional alpha-thalassemia mutation is very rare, and microcapillary hemoglobin electrophoresis with molecular examinations are required for the diagnosis of HbAdana and HbCS.
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A comparative study of the effectiveness of Pfizer-BioNTech (BNT162b2), AstraZeneca (ChAdOx1nCoV-19) and Sinopharm (BBIBP-CorV) vaccines in eliciting Cell mediated immunity in a sample of vaccinated population from Iraq.
Journal ID : AMJ-03-09-2022-10507; Author : Furqan mohammed, Ahmed sahib,
Abstract : In order to tackle COVID-19 pandemic and the emerging variants, researchers around the globe have investigated many vaccine candidates from different manufacturers, however vaccine development is not an easy task but is a top priority to restore normalcy as represented a step to achieve the desired herd immunity threshold. In this study we assessed and compared the level the peripheral mononuclear cells proliferation (PBMC) activity and in vitro INF-gamma release by the S1 spike protein stimulated T cells as they represent cellular immunity triggered from each vaccine against SARS-CoV2 infection in 123 vaccinated supposedly not infected subjects, by using Microculture tetrazolium assay (MTT) proliferation assay and an ELISA technique for the assessment of INF-gamma level in a cell culture supernatant. This study findings indicated that there was significant variety in the elicited levels of cell mediated immunity by dual vaccination at 1month and much more sustained different levels of cellular immunity among the studied previously mentioned vaccines by month8. Interestingly, both the PBMC proliferation percentage and the concentration of the in vitro IFN-y release, which represent the cellular immunity to SARS-CoV-2, were remarkably higher in 8 months than in 1month post-2nd dose vaccination groups of the three vaccines studied in this study (P<0.0001). For the PBMC proliferation percentage, AstraZeneca vaccine induced much higher proliferation percentage than Pfizer and Sinopharm (P<0.01) which both showed very close PBMC proliferation (P>0.05). For the concentration of the in vitro lFN-y release, again AstraZeneca induced distinguishing higher levels than Sinopharm and Pfizer groups (P<0.0001); nevertheless, unlike the trend found with the PBMC proliferation, Pfizer group showed significantly higher concentration of the in vitro lFN-y release than Sinopharm group (P<0.05). Moreover, the cellular immune response to all three vaccines studied showed no relationship with age, sex, and comorbidities of the vaccinated population of the study. Taken together, AstrZeneca showed superior effect on inducing robust cellular immunity followed by Pfizer vaccine, while Sinopharm showed minimal cellular immune response induction. And for all vaccines studied, the cellular immunity increased with time over 8 months after vsccination.
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Association between stress and caries experience in primary schoolchildren
Journal ID : AMJ-02-09-2022-10506; Author : Assis. Lecturer. Shahad Jamal,
Abstract : Stress can make you more susceptible to tooth caries through four different processes. According to research, adolescents are more likely to acquire poor body image, disordered eating habits, and high levels of Stress. Students experience stress due to competition and the massive quantity of material they must learn in a short period of time; studying for and taking examinations are the most frequent causes of academic stress. The goals were to examine caries experience in connection to perceived stress in children aged 6 to 12 years. A cross-sectional study will carry out involving a sample from the Pediatric Dentistry department of Al-Farahidi University, Faculty of Dentistry. The questionnaire included demographic information as well as the Perceived Stress Scale (PSS). Using the WHO's (1997) diagnostic standards for caries for missing, decayed, and filled teeth, dental caries status was examined (DMFT). Dental caries was 49.5% prevalent. The average DMFT was 14.3%. Weak (r=o.37o) (p Read more →
Effect of surface treatment on bond strength of new fiber post system (Rebilda GT) using different luting agents.
Journal ID : AMJ-02-09-2022-10505; Author : Emad F. Alkhalidi, Alaa E. Dawood,
Abstract : The aim of the present study was to evaluate the push-out bond strength of Rebilda bundle fiber posts cemented using different luting cements. Roots of thirty single-rooted mandibular first premolars were used in the present study. The root canals were instrumented using Protaper files and obturated with size X3 guttpercha. A space for the post was created by removing the gutta-percha from the coronal and middle thirds of each root using peeso reamers leaving 5mm apically to maintain apical seal. The roots were randomly divided into three groups (10 each). Ten roots were filled by Rebilda bundle fiber posts cemented according to the manufacturer instructions using Rebilda DC kit. Ten roots were filled by Rebilda bundle fiber posts cemented with self-adhesive resin cement. Ten roots were filled by Rebilda bundle fiber posts cemented with resin-modified glass-ionomer cement (GIC). Each root was cut into three 2mm-thick slices (cervical, middle and apical) and 30 specimens were prepared for each group. The slices were marked and labelled to ensure that the load is applied apico-cervically. Universal testing machine was used to measure the push-out bond strength. The push-out bond strength of the posts at the cervical root slices was significantly higher than the push-out bond strength of the posts at the middle and apical root slices. For the cervical and middle root slices, there were no significant differences between bond strength values of the posts cemented using Rebilda DC kits and the posts cemented using self-adhesive resin cement. The use of resin-modified GIC for posts cementation produced the lowest push-out bond in comparison with the other luting agents. It might be possible to recommend the cementation of bundle fiber posts using self-adhesive resin cements (with-out adhesive bonding agent) or resin-modified GIC.
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Evaluation of The Antibacterial Activity of the Alcoholic Extract of Nasturtium officinale (watercress) with Calcium Hydroxide against Enterococcus faecalis Isolated from Root Canal
Journal ID : AMJ-02-09-2022-10504; Author : Mustafa W. Abdul Kareem, Zainab Abdul jabbar Al-Dhaher,
Abstract : Herbal extracts exhibited a worth noticed antimicrobial activity against wide range of microorganisms. Apparent worldwide interest in the production of high value phytochemicals, this new approach of using natural remedies termed phytotherapy or ethnopharmacology. Root canal treatment protocols require the application of effective intracanal medicaments especially in cases with infected or previously treated canals in order to eradicate resistant microorganisms and maximize the success rate of the treatment. Nasturtium officinale is a plant with documented beneficial properties. Many studies investigated its antimicrobial properties and the results were positive. The aim of the study was to investigate the antibacterial activity of the alcoholic extract of Nasturtium officinale (watercress) alone and in combination with calcium hydroxide against Enterococcus faecalis as intracanal medication. Enterococcus faecalis is widely recovered from infected canals and regarded the most commonly isolated bacterial species from failed treated cases. The sensitivity of this bacteria to different concentrations of alcoholic extract of Nasturtium officinale was determined by using agar well diffusion method in comparison to calcium hydroxide paste. The minimum bactericidal concentration (MBC) of the tested extract against the isolated bacteria was obtained by agar plate method. Another experiment involving testing the combination of the extract with calcium hydroxide was evaluated and compared to calcium hydroxide paste with iodoform. The results of the study were promising and the extract exhibited an antibacterial activity against Enterococcus faecalis by formation of growth inhibition zones. The highest concentration tested (20 mg/ml) demonstrated the largest diameter of inhibition zones in Muller Hinton Agar plates. The studied combination with calcium hydroxide revealed a positive reaction. In conclusion, alcoholic extract of Nasturtium officinale proved to have effective antibacterial activity against Enterococcus faecalis and the combination led to enhancement of the antibacterial activity of calcium hydroxide.
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Evaluation of horizontal alveolar bone augmentation with mandibular bone block harvested from retromolar region using the split bone block technique
Journal ID : AMJ-02-09-2022-10503; Author : Mustafa Jasim Mohammed, Consultant Dr. Waleed Khalil Ismail,
Abstract : Reconstruction of alveolar defects after tooth loss is one of the biggest challenges in implant dentistry, to augment bone defects grafts of various origins have been used, the mode of graft integration depends primarily on its origin and composition. Among graft material used is the autogenous bone, which considered the gold standard for augmentation due its osteoinductive, osteogenic, osteoconductive with significant regenerative capacity over all other grafts. Intraoral sources of autogenous bone are considered the preferred donor site, due to proximity of donor and recipient sites, convenient surgical access, low morbidity, and elimination of a hospital stay. Severe alveolar defects necessitate using sufficient quantity of structurally resistant bone block for reconstructions, cortico-cancellous bone block grafts suitable for two- or three- dimensional reconstruction of these defects can be harvested only from mandibular symphysis and retromolar area. Radiographic evaluation of the outcomes of horizontal defect reconstruction with autogenous bone block harvested from retromolar area in terms of amount of horizontal bone gain and graft density four months postoperatively. This study included 10 patients for reconstruction of horizontal ridge defect using autogenous bone block harvested from retromolar region, the patients were treated at the oral and maxillofacial surgery unit of Al-Yarmouk teaching hospital and private clinic during the period from January 2020 to October 2021, the age of patients ranged from 20 to 53 years old, all patients were medically fit to undergo a bone grafting procedure. Cone Beam Computed Tomography was used for assessment of bone density and horizontal bone width pre-operatively and 10 days, 4 months post-operatively. Post-operative complications were assessed and recorded during the follow-up period. In this study, the females’ percentage was higher than males (70% versus 30%). The mean of the pre-operative width of alveolar defect was (2.54 ± 0.42) mm, after 4 months the mean of bone width gain was (4.480 ± 0.823) mm. The density of the pre-augmentation site measured with a mean of (784.8 ± 183.8) HU, then after 4 months of bone grafting procedure the density of grafted area also measured, the mean was (666.8 ± 106.4) HU. All patients developed swelling post-operatively and resolved gradually, 90% of patients complained of pain during the first week postoperatively, while only (10%) suffered from sensory disturbance for 2 weeks after the operation. Mandibular ramal bone block used according to the split block technique is a predictable method for augmentation of sever horizontal defects, autogenous bone grafts remain the gold standard of grafting materials, Cone Beam Computed Tomography is recommended, as these scans provide precise information about the thickness of bone and position of inferior alveolar nerve, the use of piezo surgery unit led to precise and clean harvest graft with minimal wastage of bone, and the overall morbidity of mandibular block for ridge augmentation is minimal.
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Role of Mirabilis jalapa on biochemical and reproductive hormones in experimental induced PCOS in female rats model.
Journal ID : AMJ-02-09-2022-10502; Author : Zainab Abbas Abed AL- Khafaji, Fouad Kadhim Gatea,
Abstract : Polycystic ovarian syndrome (PCOS), also known as Stein-Leventhal syndrome, is a diverse endocrine disorder that affects many women around the world who are of reproductive age. Prior to menopause, around one in ten women develop PCOS and associated problems. Examine the impact of Mabilisjalapa root extract on biochemical markers (Adiponectin and serum blood glucose), hormones (FSH, LH, testosterone, and estrogen), and induced polycystic ovarian syndrome in rats. Also compare the impact of Mabilisjalapa root extract with that of metformin. Female rats were treated for 21 days with 0.4 mL of oral letrozole (5.3 mg/kg) before receiving a dose of Metformin (500 mg/kg) for the first group, a high dose of Mabilisjalapa (600 mg/kg) for the second group, a low dose of Mabilisjalapa (400 mg/kg), and a combination of (300 mg/kg) from Mabilisjalapa and (250 mg/kg) from metformin. Compared to the induction group, the Mabilisjalapa treated group had reduced levels of glucose, testosterone, and LH, but higher levels of adiponectin, estradiol, and FSH. In comparison to metformin, Mabilis Jalapa treatment groups reported greater outcomes in the improvement of PCOS symptoms in female rats.
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Key Strategie for Expanded Hospital Through Mediation Exploration Nurse-Patient
Journal ID : AMJ-02-09-2022-10500; Author : Iwan Ardian, Nursalam, Ahsan, Nutrisia Nu’im Haiya, Intan Rismatul Azizah,
Abstract : The hospital is one of the places where nurses and patients interact, which requires comfort in the interaction, so a new strategy is needed, through increasing patient satisfaction, the number of hospitals that exist makes it difficult to expanded. Good nurse performance can increase patient satisfaction, which makes it the key to expanding, while the nurse's own performance is influenced by various factors within the nurse. The purpose of this study was to find a key strategy to expand the hospital's through exploration of patient nurse mediation. An analytical correlation study with a cross-sectional design using a random sampling technique with a total sample of 134 respondents was conducted. Somers'd test, lamda test and the ordinal logistic regression test were used in the model description and data analysis. Nurse education has a significant influence on the four factors of nursing and the age of nurses does not have a significant effect on the four factors of nursing, then it shows that the four factors of nursing have a significant influence on patient satisfaction, with the value of nurses' knowledge (p value 0.002; r value 0,525; OR 1,9), and the value of nurses' personality (p value 0.000; value r 0,676; OR 24,7), the value of nurse competency (p value 0.000; r value 0,573; OR 22,8), and the value of the nurse's personality variable (p value 0.000; r value 0,543; OR 3,7).The key strategy to expand the hospital is to increase the four nurse factor indicators (knowledge, attitude, competence, and personality of nurses), which are proven to have a significant effect on increasing patient satisfaction.
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The Effect of using an Educational Program with Aids in Learning the Effectiveness of Free swimming for Student
Journal ID : AMJ-02-09-2022-10499; Author : Yaqoub Abd Zaid Kazem, Mazin Hadi Kazr,
Abstract : The importance of the research is crystallized in the effect of using an educational program in learning the effectiveness of free swimming for students. The problem of the research lies in the weakness in the speed of learning and mastery of free swimming among students, and from here came the researcher the idea of learning free swimming for students using auxiliary tools The educational program, that the good use of auxiliary tools contributes to A significant limit in the student’s ability to learn speed, master the skill of swimming, reduce the degree of fear of water, feel calm and increase self-confidence, and it helps in shortening the time allocated to learning the effectiveness of free swimming. The research aims to identify the effect of using an educational program with tools to help learn the effectiveness of free swimming. For students, and to identify the effect of the educational program with tools in learning the effectiveness of free swimming for students, as for the research hypotheses, there is an effect in the use of the educational program with tools to learn the effectiveness of free swimming for students. The researcher used the experimental method by designing the two equal groups (experimental and control) with a pre and post test as it fits with the nature of the research problem. The research community included the students of the first stage - Department of Physical Education and Sports Sciences - College of the Future University, which numbered (200) students, and students were also excluded those who can swim, numbering (140) students, as well as students absent from taking tests and measurements and their number (30), as well as the exclusion of the students participating in the two exploratory experiments and their number (10) students, bringing the number of the sample to (20) students, and thus the sample constitutes (45%) ) from the original community, and they were divided equally into two groups, and for each group (10) students, they were divided into two control and experimental groups using a lottery. The educational program was applied on (2/3/2022) for a period of six weeks with two educational units per week on (Saturdays and Wednesdays). The educational units included (4) skills that are among the basic skills in learning the effectiveness of free swimming, which are (flow with the movement of the legs, breathing, flow with the movement of the arms, free swimming in full). After completing the educational units, the data was processed using the (spss) system. The effect of using an educational program with auxiliary tools in reducing psychological stress is better than the program followed by the teaching staff. Positive effect in reducing the level of psychological stress, and one of the most important recommendations is the need to learn the effectiveness of free swimming for its contribution to reducing the level of psychological stress, the need to use auxiliary tools continuously and according to the stage of learning the effectiveness of free swimming, not to allow the learner to practice swimming while he is in a poor psychological state.
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