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Azerbaijan Medical Journal

(ISSN: 0005-2523)

Azerbaijan medical journal (ISSN: 0005-2523) - is a scopus indexed journal since 1961. The publisher of the journal is Izdatel'stvo Elm by WHO Office in Azerbaijan. Azerbaijan medical journal (AMJ) is also UGC approved. The journal publishes general medicine, health science, psychological, pharmaceutical journals and so on. Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Tobacco Science and Technology Zhenkong Kexue yu Jishu Xuebao/Journal of Vacuum Science and Technology Kongzhi yu Juece/Control and Decision Changjiang Liuyu Ziyuan Yu Huanjing/Resources and Environment in the Yangtze Valley

Aim and Scope

Azerbaijan Medical Journal

Azerbaijan Medical Journal (ISSN: 0005-2523) - is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to. Zhongguo Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of China University of Petroleum (Edition of Natural Science) Teikyo Medical Journal Wuhan Ligong Daxue Xuebao (Jiaotong Kexue Yu Gongcheng Ban)/Journal of Wuhan University of Technology (Transportation Science and Engineering) Zhonghua yi shi za zhi (Beijing, China : 1980) Agricultural Mechanization in Asia, Africa and Latin America International Medical Journal Technology Reports of Kansai University Asia Life Sciences Open Access Journals Tagliche Praxis

Anatomy Physiology Biochemistry Pharmacology Pathology Forensic medicine Microbiology Community Medicine Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases Anaesthesia Cancer research Neurosurgery Orthopedics Gastroenterology Neurology Nephrology Medical education Orthopaedics Paediatrics Reproduction Cardiology Diabetes Surgery Nursing Otolaryngology Dental Psychology Anesthesiology Dermatology Endocrinology Hepatology Urology Venereology Psychiatry Biotechnology Pharmacy ENT Pharmaceutical Chemistry Pharmaceutical Analysis Pharmaceutics Pulmonology Pharmacognosy Pharmaceutical Phatmaceutical Technology Biopharmaceutics Pharmacokinetics Pharmacodynamics Industrial Pharmacy Drug Design Quality Assurance Drug Regulatory Affairs Phytochemistry Drug Delivery Systems Pharmaceutical Nanotechnology Pharmaceutical Microbiology Hospital Pharmacy Clinical Pharmacy Pharmacy Practice Drug Discovery Drug Metabolism Toxicology Clinical Research Pharmacogenomics Phrmacoinformatics Pharmacovigilance< Life Sciences like Chemistry Biomedical Sciences Microbiology Immunology Forensic Epidemiology Oncology Biomedicine Dentistry Physiotherapy Gynaecology Dermatoepidemiology Neuroscience Ophthalmology Sexology Osteology Kinesiology Angiology/Vascular Medicine Critical care Medicine Haematology Infectious Diseases and Vaccinology Bariatrics Pharmacy and Nursing Pharmacognosy and Phytochemistry Radiobiology Clinical immunology Clinical and Hospital Pharmacy Cell Biology Genomics and Proteomics Healthcare Services Healthcare Management Bioinformatics and Biotechnology Geriatric Medicine Bulletin of National Institute of Health Sciences Journal of the Austrian Society of Agricultural Economics Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Tobacco Science and Technology Zhenkong Kexue yu Jishu Xuebao/Journal of Vacuum Science and Technology Wuhan Ligong Daxue Xuebao (Jiaotong Kexue Yu Gongcheng Ban)/Journal of Wuhan University of Technology (Transportation Science and Engineering) Zhonghua yi shi za zhi (Beijing, China : 1980) Zhongguo Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of China University of Petroleum (Edition of Natural Science) Teikyo Medical Journal Kongzhi yu Juece/Control and Decision Changjiang Liuyu Ziyuan Yu Huanjing/Resources and Environment in the Yangtze Valley

Latest Journals

Azerbaijan Medical Journal

Agricultural Mechanization in Asia, Africa and Latin America International Medical Journal Technology Reports of Kansai University Asia Life Sciences Open Access Journals Tagliche Praxis Bulletin of National Institute of Health Sciences Journal of the Austrian Society of Agricultural Economics
Risk factors of mortality among patients with Coronary Artery Bypass Grafting attending Cardiac Center of Erbil City; A cross-sectional study.
Journal ID : AMJ-13-03-2022-10170; Author : Shwan Othman Amen, Banan Rasool, Hewa Mustafa Muhammad, Anas Abdullah Rasool, Aya Nasih Mohammad, Bareq Sabeeh Hashim, Dina Shehata, Salah Yousif Hassan, Attaullah Ahmadi, Don Eliseo Lucero-Prisno III,
Abstract : Coronary artery bypass grafting (CABG) is a major surgical operation where atheromatous blockages in a patient’s coronary arteries are bypassed with harvested venous or arterial conduits. Post-CABG mortality has been associated with multiple patient factors such as advanced age, preoperative renal dysfunction, diabetes, low preoperative Ejection Fraction (EF), stroke, carotid artery disease, dysrhythmias, concomitant valvular disease and multiple other comorbidities. To assess the mortality rate and discuss the possible risk factors associated with mortality following CABG. A cross sectional study was conducted in the Cardiac Center in Erbil, Kurdistan region of Iraq from June 2020 to March 2021. Data was collected from case files of 200 patients in the hospital records and follow up data was obtained after a 6-15-month period by interviewing the patients directly. Data were analysed using the Statistical Package for Social Sciences version 23 (SPSS, IBM, Armonk, NY, USA). The mortality rate after CABG was 8.5% in the study duration, with the majority being in the 50-59 age group. Female gender, left ventricular dysfunction, hyperlipidemia, double vessel disease and triple vessel disease, valvular disease and concomitant valve surgery were identified as risk factors for mortality in the postoperative period. More efforts should be directed towards preventing and controlling cardiovascular risk factors to decrease the prevalence and impact of CAD in our community.
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Epidural Varicose Vein Mimic Disc Prolapse and Causing a Severe Radicular pain: A Case series
Journal ID : AMJ-10-03-2022-10169; Author : Ammar Najim Abood,
Abstract : Venous varicose of the epidural is regarded as an infrequent cause of the root of the nerve, impingement, and theca sac compression that cause the radiculopathy of the lower limb. The essential purpose of the study is to focus on this problem during the process. It also aims to focus shed a light on using magnetic resonance imaging (MRI) before the operation. This research also attempts to evaluate the outcome of the surgery. Symptoms of epidural varicose with radiculopathy are rare and the diagnosis is often inaccurate by preoperative clinical examination and radiology investigations. Thus, in many cases the diagnosis is made intra- operatively. The 12 cases were age between 34 and 51 years old were 7 females and 5 males who have consulted our outpatient clinic from 2014 to 2020 complaining from acute radicular pain in the lower back and down to lower limb. MRI was done for them and showed disc herniation. Intra operatively revealed an abnormal dilatation of epidural vein impingement on nerve root and spinal cord. We initiated a thermo coagulation of the epidural vein from proximal to distal ends at disc level and used gel foam patch to control bleeding that was removed all at the end of operation. Then, coagulation ablation was performed. The operation resulted in relief of symptoms and neurologic recovery occurred during follow up period. According to our cases and previously published case reports, the outcome is good with recovery of neurological signs and symptoms that can be obtained by coagulation ablation of epidural varicose vein.
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CHEMICAL COMPOSITION AND ANTIBIOTIC CONTENT OF FARMED HONEY IN QUANG NGAI PROVINCE
Journal ID : AMJ-10-03-2022-10168; Author : Thi Tuong Vy Nguyen, Huu The Nguyen, Van Giang Tran,
Abstract : To determinate the purity and antibiotic composition on farm-raised honey in Quang Ngai province. Acacia honey is harvested in Minh Long district, Quang Ngai province during the rainy and dry seasons. The chemical composition and antibiotic content in final products are accurately low in the limit of detection (LOD) and limit of quantitation (LOQ). They are validated to be technically suitable for consumer according to the guidelines provided by the Association of Official Analytical Chemists (AOAC) and the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH). The result of analysis of chemical components of the studied honey shows that the C4 sugar content ranges from 3.1 to 5.2%, which is within the range of pure honey. The Fluoroquinolones Antibiotic Group, including Ciprofloxacin, Danofloxacin, Difloxacin, Enoxacin, Enrofloxacin, Flumequin, Gatifloxacin, Levofloxacin, Lomefloxacin, Marbofloxacin, Nalidixic Acid, Norfloxacin, Orbifloxacin, Oxolinic Acid, Pefloxacin, Sarafloxacin, as well as some other antibiotics such as Sparfloxacin, Chloramphenicol, and Streptomycin, are almost undetectable. Research results indicate that farm-raised honey is safe for consumer.
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Role of magnetic resonance imaging as a modality in preoperative evaluation of perianal fistula.
Journal ID : AMJ-09-03-2022-10167; Author : Abhishek Nayak,MBBS, DNB (Radiology), Senior resident, Department of Radiology Apollo Hospital, Bhubaneswar., Nihar Ranjan Mohanty - MBBS, MD, Associate Professor, Department of Radiology, Kalinga institute of Medical Sciences, Bhubaneswar., Madhusmita Mohanty – MBBS, MD Assistant Professor, Department of Pathology, Kalinga institute of Medical Sciences, Bhubaneswar., Bikash Agrawala – MBBS,MD, Senior consultant, Department of Radiology, Apollo Hospital, Bhubaneswar., Sashibhusan Dash-Ph.D Scholar and Senior Research Fellow,Department of Oncopathology,Acharya Harihar Post Grduate Institute of Cancer,Cuttack.,
Abstract : Magnetic resonance imaging (MRI) has emerged as the investigation of choice for the preoperative evaluation of perianal fistulas. The objectives of this study were to assess the usefulness of MR imaging in the evaluation of various grades and types of perianal fistula, correlate with intraoperative findings, and evaluate its role in postoperative recurrence. A prospective observational study was conducted over a period of 18 months on 55 patients referred with suspicion of perianal fistula. Preoperative MR fisulography scanning findings of patients were analysed and compared with intraoperative findings. Intraoperative findings were consistent with radiological description for detection of tracts. MRI could correctly diagnose primary tracts in 53 out of 55 patients and branched tracts in 19 out of 21 cases. For the detection of abscesses (14% of cases) and horse shoe components (7% of cases), MRI showed 100% concordance with surgery. High concordance was noted between MRI and surgical findings in relation to both St James and Park’s classifications, with p values of 0.01 and 0.0002 respectively. In the detection of internal openings, MRI showed high sensitivity (96%), specificity (83%), and positive predictive value (94.5%) with respect to surgical finding. Preoperative MRI showed reduced postoperative recurrence of fistula with only 2 cases out of 55 showing recurrence after 1 year. Preoperative MR fistulogram improves diagnostic effectiveness in the assessment of fistulous tract courses by demonstrating the location of the fistula in relation to anal sphincters and correctly identifying internal openings, branch tracts, abscesses, and horse shoe components.It also reduces post-operative recurrence.
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Phytochemical Properties and Antimicrobial Activities of Some Medicinal Plants in Cebu, Philippines
Journal ID : AMJ-09-03-2022-10166; Author : Esperanza M. Del Fierro,
Abstract : Detection of the phytochemicals in medicinal plants and determining their antibacterial property can lead to drug discovery and development. This study performed ethanolic leaf extract of the ten medicinal plants to identify bioactive compounds and the sample's antibacterial activities. The selected medicinal plants were Pandanus amaryllifolius, Asplenium nidus, Corchurus olitoroius, Schefflera odorata, Adonidia merrillii, Artocarpus altilis, Bixa orellana, Mentha arvensis, Polyscias scutellaria, and Camptostemon philippinensis. Phytochemical screenings of the plant extracts employed standard methods. The potency of the ten sample extracts was obtained through the disc diffusion method against the gram-positive bacteria Staphylococcus epidermidis and Bacillus cereus, and gram-negative bacteria Escherichia coli and Serratia marcescens. Results showed that all plant extracts contained saponins, tannins, coumarins, and glycosides. However, bioactive compound steroids are present in the extracts of P. amaryllifolius, A. nidus, A. merrillii, A. altilis, and B. orellana. Antimicrobial activities of the plant extracts revealed that A. nidus has the highest potency against S. marcescens at 10mg/ml and its minimum inhibitory concentration (MIC) at 5mg/ml with 18.67.33mm 16.33mm zone of inhibition, respectively. Escherichia coli showed considerable susceptibility to S. odorata extracts at the 5mg/ml MIC with 9.83mm inhibition. Thus, these are implications that the plant extracts containing specific phytochemicals beneficial to human health to develop into potential medicine against the susceptible bacteria.
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Anti-proliferative activity of Cassia angustifolia in Breast Cancer Cell Line
Journal ID : AMJ-06-02-2022-10164; Author : Walaa Najm Abood,
Abstract : Medicinal plant was wildly used at recent year for treated many diseases instead of chemical drugs because of less in side effect. Cassia angustifolia leaves extract was investigated in this study as anti-proliferation agent for type of breast cancer cell. C.angustifolia (CA) ethanol leaves extract and its fractions (CAF) were evaluated in vitro for the MCF7 cell line and MDA-MB-231 cell line as anti-proliferation. The cells were treated in different doses for CA and CAF at 24h and 28h. The treated cells were stained with AO/EB stain to evaluated apoptosis effect of CAF. GCMS method was used to identify active component in the CAF that give highest anti-proliferation activity. Leaves extract of C.angustifolia was identified as anti-proliferation for MCF7 cell line and MDA-MB-231 cell line. The result was revealed that CAF1 was had highest inhibition percentage for both cells, in (76.73 ± 0.23) % for MCF7 cell and (70.49 ±2.6) % for MDA-MB-231cell. Apoptosis percent present for treated MCF7 cell at 24h and 48h was (84.32 ±22.42) and (72.32 ± 25.08) respectively. And for treated MDA-MB-231cell was (60.16 ± 40.13), (65.31 ± 30.28) respectively for the highest dose 1000 µg/mL. GCMS analysis was identified 23 active component as 2-Pentanone, 4-hydroxy-4-methyl- and 2H-Pyran, 2-(2-heptadecynyloxy), Hexadecanoic acid, methyl ester, Oxalic acid, Phthalic acid, di(2-propylpenty, 2-Pentadecanone, 6,10,14-trimet,and Carbonic acid, decyl tridecyl ester, 2-Tetradecynal, 4-hydroxy-, Tritriacontane, Tricosane, Hexadecanoic acid, methyl ester and Hexadecanoic acid, ethyl ester, Pentadecanoic acid, 14-methyl ester, Heptadecanoic acid, 16-methyl- , Methyl 8-oxooctanoate, Hexadecyl propyl ether, Undecanal, Octadecanoic acid, ethyl ester, 3-Methyl-4-(phenylthio)-2-prop-, dimer of Coleon F. In conclusion that C.angustifolia frication1 for ethanol leaves extract has anti proliferation and antitumor effect on the breast cancer by enhanced apoptosis pathway that lead to programmed cell death for cancer cell and prevent metastasis of its. For that CAF1 could be as new drug to treat aggressive breast cancer.
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Wound Remodelling Anal Trauma in Wistar Rat After Application of Combination Platelet Rich Plasma (PRP) and Stromal Vascular Fraction Cells (SVFs)
Journal ID : AMJ-09-01-2022-10159; Author : Ades Santa Satria, Sulmiati, Nita Mariana, Andi Alfian Zainuddin, Fonny Josh, Sarachaswaty L. Laiding,
Abstract : Anal trauma is a very rare condition. Although rare, anal trauma has the potential to cause anal stenosis, ectropion, or incontinence that can interfere with a person's quality of life. This problem can also be caused after surgery on the anus, which is the primary modality of this case. More severe complications can include peritonitis, sepsis, to death. Therefore, an effective non-invasive alternative therapy is urgently needed in healing anal trauma. This research was conducted using an experimental laboratory method on male Wistar rats using a post-test control group consisting of three groups treated with PRP+βSVF (each, n=4), three groups treated without PRP+SVF (each, n=4), and one control group (sacrifice on day 0). All the treatment groups were sacrificed on days 1, 7, and 14 post-treatment. The anal trauma was made through a longitudinal incision from distal to proximal with a depth of 5 mm from serosa to intraluminal. TGF-β was measured using the ELISA method. Data represented the mean +/- standard deviation and was further analyzed by the one-way Anova test. There was a significant difference between the mean TGF- β levels in the intervention group and the control group on day 1 (31.07±1.65 vs. 25.6±1.02, p=0.01) and day 14 (31.47±0.51 vs. 27.42±1.17, p= 0.01). Meanwhile, on day 7, there was no significant difference (29.37±2.27 vs. 26.44±2.61, p=0.18). A combination of SVF and PRP effectively accelerates the healing process of anal trauma in vivo, which is assessed based on TGF-β levels.
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DIARRHEAL INFECTIONS IN UKRAINE: CURRENT EPIDEMIOLOGICAL SITUATION
Journal ID : AMJ-02-12-2021-10158; Author : Malysh Nina, Chemych Mycola, Doan Svitlana, Rodyna Roman, Chorna Inna,
Abstract : Purpose of the study on the background of the analytical study of the incidence of diarrheal infections in Ukraine under the current conditions, to determine the factors influencing epidemic situation. The processes of globalization, fundamental changes in nutrition and water consumption contributed to the fact that the significance of individual infection sources, ways of invader transmission, etiological structure of diarrheal infections changed. Epidemiological and statistical research methods are applied. Statistical processing of the study outcome is carried out using software application Microsoft Office Excel 2010, Statstica 6. The epidemic situation with diarrheal infections in Ukraine is characterized by a low incidence of typhoid fever, shigellosis, stable incidence rates without the downward trend, salmonellosis, high incidence of diahrreal infections of specified etiology and diahrreal infections of unspecified etiology. The most complicated epidemic situation is observed in economically most developed regions of the country. Most diarrheal infections outbreaks are connected with catering establishments 36.5 % and with children educational establishments 26.1 %. In the region with the highest shigellosis and salmonellosis incidence direct strong correlation relationships are established between the incidence and population, density, natural population movement. The oblasts with the highest diahrreal infections of specified etiology, rotaviral enteritis, diahrreal infections of unspecified etiology incidence are at least provided with water resources and have problems with provision of high-quality drinking water.
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Modern approaches to assessment toxicity of xenobiotics
Journal ID : AMJ-18-09-2021-10153; Author : Garaev, Huseyngulieva,
Abstract :

Consumers are exposed to a diversity of chemicals in all areas of life. Air, water, soil and food are all unavoidable components of the human environment. Each of those elements influences the quality of human life, and each of them may be contaminated. We are exposed to toxic or potentially toxic compounds in many ways in our daily lives and toxicology is clearly a subject of great importance for society. This becomes apparent when we look at the types of poisons and the ways in which we are exposed to them. Indeed, the categories cover virtually all the chemicals one might expect to encounter in the environment. After consideration of this, one might well ask “Are all chemicals toxic?” Phrase as an answer: “There are no safe chemicals, only their safe use”. Xenobiotics are defined here as those compounds, both organic and inorganic, produced by human beings and introduced into the environment, as well as into the food chain at concentrations that cause undesirable effects. Xenobiotics in the food chain are monitored in two forms: by testing – the objective of which is to discover unsuitable foodstuffs in the consumer’s network, and by monitoring – to obtain objective information about environmental components contamination and to harmlessness health of available foodstuffs.

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Characteristics of anxiety and depressive manifestations in patients with acute myocardial infarction taking into account their personal accentuations
Journal ID : AMJ-18-09-2021-10151; Author : Boiko, Kachur, Ajala, Bodnar, Zhyvotovska,
Abstract :

The main objective of the study was to find out prevalence of depression and anxiety symptoms in the population of patients with AMI with ST-segment elevation (STEMI), treated with primary PCI (pPCI). Secondary target indicators included the incidence of sleep disorders and loss of interest in sex. The project enrolled 79 consecutive patients with the first AMI, aged <80 years (median 61 years, 21.5% of women) with a follow-up period of 12 months. Symptoms of depression or anxiety were measured using the Beck Depression Inventory II tests (BDI-II, cut-off value ≥14) and Self-Rating Anxiety Scale (SAS, cut-off ≥ 45) within 24 hours of pPCI, before the discharge, and in 3, 6 and 12 months). Results with the value p<0.05 were considered as statistically significant. The BDI-II positivity was highest within 24 hours after pPCI (21.5%) with a significant decline prior to the discharge (9.2%), but with a gradual increase in 3, 6 and 12 months (10.4%; 15.4%; 13.8% respectively). The incidence of anxiety showed a relatively similar trend: 8.9% after pPCI, and 4.5%, 10.8% and 6.2% in further follow-up. Patients with STEMI treated by primary PCI have relatively low overall prevalence of symptoms of depression and anxiety. A significant decrease in mental stress was observed before discharge from the hospital, but in a period of one year after pPCI, prevalence of both symptoms was gradually increasing, which should be given medical attention.

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