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Volume - 63 , Issue 02
28 Feb 2023

Azerbaijan Medical Journal

(ISSN: 0005-2523)

Azerbaijan medical journal (ISSN: 0005-2523) - is a scopus indexed journal since 1961. The publisher of the journal is Izdatel'stvo Elm by WHO Office in Azerbaijan. Azerbaijan medical journal (AMJ) is also UGC approved. The journal publishes general medicine, health science, psychological, pharmaceutical journals and so on. Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Interventional Pulmonology Zhenkong Kexue yu Jishu Xuebao/Journal of Vacuum Science and Technology

Aim and Scope

Azerbaijan Medical Journal

Azerbaijan Medical Journal (ISSN: 0005-2523) - is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to. Zhongguo Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of China University of Petroleum (Edition of Natural Science) Tobacco Science and Technology Teikyo Medical Journal Connected Health Wuhan Ligong Daxue Xuebao (Jiaotong Kexue Yu Gongcheng Ban)/Journal of Wuhan University of Technology (Transportation Science and Engineering) Zhonghua yi shi za zhi (Beijing, China : 1980) Agricultural Mechanization in Asia, Africa and Latin America International Medical Journal Technology Reports of Kansai University Asia Life Sciences Open Access Journals Tagliche Praxis

Anatomy Physiology Biochemistry Pharmacology Pathology Forensic medicine Microbiology Community Medicine Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases Anaesthesia Cancer research Neurosurgery Orthopedics Gastroenterology Neurology Nephrology Medical education Orthopaedics Paediatrics Reproduction Cardiology Diabetes Surgery Nursing Otolaryngology Dental Psychology Anesthesiology Dermatology Endocrinology Hepatology Urology Venereology Psychiatry Biotechnology Pharmacy ENT Pharmaceutical Chemistry Pharmaceutical Analysis Pharmaceutics Pulmonology Pharmacognosy Pharmaceutical Phatmaceutical Technology Biopharmaceutics Pharmacokinetics Pharmacodynamics Industrial Pharmacy Drug Design Quality Assurance Drug Regulatory Affairs Phytochemistry Drug Delivery Systems Pharmaceutical Nanotechnology Pharmaceutical Microbiology Hospital Pharmacy Clinical Pharmacy Pharmacy Practice Drug Discovery Drug Metabolism Toxicology Clinical Research Pharmacogenomics Phrmacoinformatics Pharmacovigilance< Life Sciences like Chemistry Biomedical Sciences Microbiology Immunology Forensic Epidemiology Oncology Biomedicine Dentistry Physiotherapy Gynaecology Dermatoepidemiology Neuroscience Ophthalmology Sexology Osteology Kinesiology Angiology/Vascular Medicine Critical care Medicine Haematology Infectious Diseases and Vaccinology Bariatrics Pharmacy and Nursing Pharmacognosy and Phytochemistry Radiobiology Clinical immunology Clinical and Hospital Pharmacy Cell Biology Genomics and Proteomics Healthcare Services Healthcare Management Bioinformatics and Biotechnology Geriatric Medicine Bulletin of National Institute of Health Sciences Journal of the Austrian Society of Agricultural Economics Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Interventional Pulmonology Zhenkong Kexue yu Jishu Xuebao/Journal of Vacuum Science and Technology Wuhan Ligong Daxue Xuebao (Jiaotong Kexue Yu Gongcheng Ban)/Journal of Wuhan University of Technology (Transportation Science and Engineering) Zhonghua yi shi za zhi (Beijing, China : 1980) Zhongguo Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of China University of Petroleum (Edition of Natural Science) Tobacco Science and Technology Teikyo Medical Journal Connected Health

Latest Journals Agricultural Mechanization in Asia, Africa and Latin America International Medical Journal Technology Reports of Kansai University Asia Life Sciences Open Access Journals Tagliche Praxis Bulletin of National Institute of Health Sciences Journal of the Austrian Society of Agricultural Economics

Azerbaijan Medical Journal

Effect of Simvastatine Drug and Aqueous Extracts in Improvement Kidney Functions and Renal Histological Lesion in Hyperlipidemia Induction Experimentally
Journal ID : AMJ-23-12-2022-10961; Author : Fatima Aziz Mahdi Al-badry, Zahraa Sadiq Taher,
Abstract : The present study was designed to detect the histopathological and physiological changes in kidney which resulted from hyperlipidemia and treatment of it by simvastatin and aqueous extracts of garlic, cinnamon and mint. Fifty four for male rats were divided randomly into nine groups, the first group (control) received diet without cholesterol while the second group administrated cholesterol for inducing hyperlipidemia induction, the third group treated with simvastatin after hyperlipidemia induction, the fourth, fifth and sixth groups treated with aqueous extracts of garlic, cinnamon and mint at 75 mg / kg/day respectivelly, while the seventh eighth and ninth groups were infected by hyperlipidemia and treated with same extracts at 50 mg/kg/ day. The treatment by simvastatin and extracts of plants was continued for one month. The results of present study showed a significant increasing (P≤0.05) in indicaters of kidney functions (urea, creatinine and uric acid) in lipidemic group while these parameters were decreased significantly (P≤0.05) in treated groups with drug and extracts f plants. The microscopic examination of kidney sections in hyperlipidemia group revealed to edema, enlargement canals of renal tubules as well as absence, contraction and death of glomeruli, while the treatment by drug and plants extracts led to return normal structure for kidney.
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A new removable orthodontic and orthopedic appliances cleanser
Journal ID : AMJ-23-12-2022-10960; Author : Mohammed Thanoon Younis, Safwan Mohsen Al_Aubadi, Omar Khalid Mohammed,
Abstract : Because numerous various germs are discovered on their surface during orthodontic treatment, detachable orthodontic and orthopedic appliances cleaner demands careful hygiene. About 60 samples with dimension (45*10*1.5mm length, with thickness) were used for the color test by spectrophotometer device, and 60 samples with dimension (30*10*3mm length width thickness) were used for the hardness test by shore A hardness device. The orthodontic appliance should be cleaned after each meal time for about half an hour three times per day to stay clean without stain, food accumulation, and to keep consequences of staind appliance away like gingivitis and candidiasis sore throat, So to make the cleaning simulation cycle, we soaked these samples in cleanser solutions for ½ hour three times per day after each cleaning once we put the samples in r.o. water. every day we repeat the cleaning procedure for about two months. For the color test, We measured the absorbance at the beginning of the study, and after two months maximum absorptions of visible light by acrylic resin occurred at the wavelength (345nm).so, for the hardness test we measure it after two months and compare it with the control solutions. The experimental results showed that the Interquartile range at the Preclean color for (hydrogen peroxide 6%) was 0.32 compare to water and tablet (0.11, 0.10) respectively, compare to the Post-clean color (0.28, 0.20), So the results showed the Interquartile range of Hardness about (4.71, 3.95) respectively for two groups (4gm soda+ 4.5 g citric and 2gm soda+ 6.14 g alum), whilst 3.15 for three groups (2gm soda+ 4.5 g citric, 1gm soda + 6.14 g alum and 50%H2O2), When the comparison of (precleaning and post-cleaning color) by using Wilcoxen signed ranks test between all groups, as well as results showed (P-value <0.05) for all groups except water as (P-value >0.05), so results of the current study showed significantly (p<0.05), when Comparing solution post-cleaning color with water and tablet by using of Mann whiteny test.so the tablet versus water there was a change in color and the difference was statically significant (p-value = 0.07 > 0.05). Color: Soda+ citric acid solutions of different conc. Of soda have no diverse effect on the color of acrylic resin. Soda + alum increase color density, H2O2 decrease color density (bleaching effect), In comparison with water and tablet. Hardness: Both of them (Soda +citric, Soda+alum) have no diverse effect on hardness of acrylic resin, H2O2 increase hardness of acrylic resin because leach out of plastisizer. The best cleanser solution that have no effect on the color and hardness of acrylic resin speciment is (soda + citric acid) with different conc.
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Hypoglycemic Potential of Sungkai (Albertisia papuana Becc) Soaking Water in Alloxan-Induced Diabetic Rat
Journal ID : AMJ-23-12-2022-10959; Author : Dery Ade Pramana, Erma Prihastanti, Kasiyati,
Abstract : Diabetes mellitus (DM) is a chronic disease characterized by blood glucose levels that exceed normal. One alternative treatment is to use herbs that have the potential as hypoglycemic compounds. Sungkai is one of the plants used by the Dayak tribe for generations to treat diabetes. This study aims to determine whether each organ of the Sungkai plant has the potential as a diabetes drug. The parameters measured in this study were antioxidant activity and total phenolics. This study used a completely randomized design with 25 white rats (Rattus norvegicus) as diabetic animal models, which were divided into five treatment groups which included normal rat (K-), DM positive rat K(+), and DM rat + soaking water from Sungkai leaf, DM rat + soaking water from Sungkai stem, and DM rat + soaking water from Sungkai root. The data obtained were analyzed statistically by ANOVA with sequence, normality test, homogeneity, and further test using Duncan's test. The results showed that the antioxidant activity and total phenol of each part of the Sungkai plant were significantly different (p<0.05). The highest antioxidant activity is found in the leaves. Blood glucose levels of DM rats decreased after 30 days of Sungkai treatment. Sungkai plant has different antioxidant activity in each organ, and the Sungkai plant has hypoglycemic potential in overcoming diabetes mellitus.
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Efficacy of Adjunctive Intralesional Steroid Injection After Laryngeal Microsurgery of Benign Vocal Fold Lesion
Journal ID : AMJ-23-12-2022-10955; Author : Arif Surgana, Rizka Fathoni Perdana, Diar Mia Ardani,
Abstract : Benign vocal fold lesion cause alteration of lamina propria epithel then lead to dysfonia. Voice therapy is the first line treatment of benign vocal fold lesion. Low compliance affect increasing number of recurrences. Intralesional vocal fold steroid injection could be alternate adjuvant in management of benign vocal fold lesion. To assess efficacy intralesional steroid injection in benign lesion vocal fold patient those after underwent laryngeal microsurgery. Data collected from RSUD Dr. Soetomo medical records. Design of this study is retsospective descriptive analytic. We reviewed 8 medical records patients who underwent laryngeal microsurgery removal of benign vocal fold lesion and acquire intralesional steroid injection for consecutive periode Jan 2017 until Des 2018. Score assessment of VHI-10, GRBAS & fiberoptic laryngoscope reviewed before and after intralesional steroid injection. We obtain 8 medical records of patients those underwent intralesional steroid injection following laryngeal microsurgery. VHI-10 scores show significant alteration after 1 month following intralesional steroid injection (p 0.001) and 6 month (p 0.002). GRBAS scores show significant change after 1 month following intralesional steroid injection (p 0.011) and 6 month (p 0.012). Fiberoptic laryngoscopy evaluation shows 2 patients (25 %) have recurrence after 1 month. Adjuvant therapy of intralesional steroid injection have significant effect in relieving dysphonia symptoms that assessed by VHI-10 and GRBAS score. Further study is required to get better objective measurement as such as MDVP assessment and stroboscopy imaging.
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Satisfaction and Self-confidence of Students’ of 5th year in Medicine after cervical smear Simulation-based Workshop: a pre- and post-intervention comparison study
Journal ID : AMJ-22-12-2022-10954; Author : Bouchra Amaoui, Abdellah El Farouki, Slimane Semghouli, Sanae Abbaoui, Hicham Nassik,
Abstract : This study aimed to evaluate the impact of simulation as a teaching tool for the technique of the cervical-uterine smear and the announcement of the results as part of the training of 5th year students of medicine at the Faculty of Medicine and Pharmacy of Agadir (FMPA). This is a monocentric cross-sectional descriptive study. Seven sessions were held, and each session consisted of a practical workshop and two simulation sessions. Two questionnaires were used to collect the data. They focused on the evaluation of knowledge (pre-test), then the evaluation of the knowledge and skills acquired (post test) of the students. Ninety-two students participated in this training. The results showed that 78% of the learners had an improvement in their level of knowledge (p=.00001) after the session. 95% expressed apprehension before taking a cervical smear compared to 3% at the end of the session (p=0.000). In addition, learners expressed difficulties in communicating with patients, especially in the non-verbal aspect, with a significant improvement (48% at the beginning of the session vs. 16% at the end of the session (p=.00001)). Finally, all learners were willing to attend another simulation training session. This study has shown that simulation training for Pap smear and announcement consultation leads to a significant improvement in the knowledge and skills of the learners. To improve patient care, simulation-based training for Pap smear should be included in the curriculum for students as well as sessions of certified training for practicing physicians.
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Correlation between Helicobacter pylori and severity 0f Ulcerative Colitis
Journal ID : AMJ-22-12-2022-10952; Author : Fateh Al-Khaqani, Rafida M. AL-Amiri, Haider H. Jabbar,
Abstract : Ulcerative Colitis (UC), is a type of inflammatory bowel disease (IBD), recent research and studies showed an association between H. pylori infection and IBD. This study was conducted to evaluate the association between H. pylori infection and the severity of ulcerative colitis. A cross-sectional descriptive study was conducted at Fayhaa Teaching Hospital, Gastrointestinal center, Basrah, the southern part of Iraq from August 2021 to February 2022, on 52 patients with Ulcerative colitis. The included patients were categorized into two main groups according to the Helicobacter pylori stool antigen status. Before the official study conduction, a simple pilot study was conducted on 52 patients. Statistical calculations were done using Statistical Package for the Social Sciences version 25 (SPSS Inc.) and P-values <0.05 were accepted as statistically significant. The current study included 52 patients with a mean age of (31.60± 11.54), and (53.8%) of the studied population were males, the mean duration of the disease was 3.29± 2.64 years. Out of the studied groups, (53.8%) were diagnosed with H. pylori-positive antigen, and (46.2%) with negative antigen. The Truelove and Witt’s Severity Index for Ulcerative Colitis has classified the cases into three main categories (mild, moderate, and severe), the mean age and duration of the disease were slightly higher among the severe group (34.29± 12.40, 3.86± 1.67) followed by the mild group (31.44± 12.29, 3.56± 3.32). Most males developed a moderate category (72.3%), while most females were classified as a severe class (71.4%). Also, it was clearly shown that most of the patients with positive H. pylori Ag were categorized as a severe class (71.4%), and most of the negative H. pylori Ag were categorized as a mild class (48.1%). Moreover, none of the demographical or laboratory data recorded significant values (p-value <0.05). A higher percentage of ulcerative colitis patients have H. pylori-positive test. The severity of the disease increases with age and the severe course of the disease is usually associated with the male gender rather than females.
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Resveratrol Protects Retinal Ganglion Cells Against Oxidative Stress by Increasing Superoxide Dismutase-1 in Retinal Ganglion Cells After Ischemic Reperfusion Injury
Journal ID : AMJ-22-12-2022-10951; Author : Maria Debora Niken Larasati, Wimbo Sasono, Nurwasis, I Ketut Sudiana, Chrismawan Ardianto, Mercia Chrysanti, Amelia Shinta,
Abstract : Resveratrol has antioxidant, anti-inflamation, and neuroprotective effects in oxidative stress induced by ischemic reperfusion injury in eyes with IOP elevation. This study aimed to investigate the protection effect of resveratrol against oxidative stress in retinal ganglion cells. Retinal ischemia was induced by increasing intraocular pressure to 110 mmHg for 60 minutes in 20 adult male Rattus Norvegicus rats. Resveratrol (RSV) suspension of 100M in 2L PBS was injected intravitreally 3 hours after reperfusion. After 7 days, rat’s eye was enucleated. Primary SOD-1 antibody (Santa Cruz Biotechnology, Inc.) and MDA antibody (Biorbyt Ltd.) was used to determine the SOD-1 and MDA expression in retinal ganglion cells. SOD1 expression was significantly decreased between control group and both of ischemic group (p value <0.001) and MDA level was increased after ischemic-reperfusion (IR) injury (p value <0.01). Comparison between IR+RSV group and both of IR groups was increase significantly: IR0 group (p value <0.05); IR7 group (p value <0.01), respectively. There was also significant decreased of MDA expression between resveratrol group (IR+RSV) and IR0 (p=0.030), also IR7 group (p=0.006) respectively. Resveratrol protects retinal ganglion cells from oxidative stress after IR injury by increasing SOD1 expression as antioxidant enzyme and then reducing malondialdehyde as oxidative stress marker.
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The Effectiveness of Online Course about Pain Management and Local Anesthesia Methods for Undergraduate Dental Students
Journal ID : AMJ-22-12-2022-10950; Author : Enass Shamsy, Mayssoon Dashash,
Abstract : Local anesthesia (LA) is the most commonly method for pain control during dental procedures. Dentists should have the knowledge, skills and attitude about LA. Therefore, this study aimed at evaluating online course about dental pain management and local anesthesia methods used in dentistry. A total of fifty-four dental students who accepted to participate in this study were included. An online course composed of six-module was developed. Students' knowledge was assessed by comparing their learning before and after their participation using identical pre and post-test. According to Chi-Square statistics, significant difference at P < 0.05 was found between the correct answers of participants in pre-tests and post-tests which indicates that the level of learning was significantly higher after the participation of the online course. The use of online educational course is effective in developing dental students' knowledge of dental pain management and the local anesthesia methods used in dentistry.
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Satisfaction of Pregnant Women with Obstetric Care Services in the Hospital
Journal ID : AMJ-22-12-2022-10949; Author : Sajidah Saadoon oleiwi, Haqi Ismael Mansoor, Zaki Sabah Musihb,
Abstract : Maternal satisfaction considers one of the most common measurements to report the outcome for the quality of care and must increase to enhance the efficiency and quality of care during the periods of antenatal, natal, and postnatal to give high-quality care services to the maternal. To assess women's satisfaction to the obstetric care services in maternity hospitals in most areas of care such as Labor unit, Maternity unit. A descriptive design that is adequately constructed to measure women's satisfaction with obstetric care. A non-probability (purposive) sample of (50) women attending government hospitals served as the study's main data collection method. The questionnaire included two main parts. (demographic information, and Satisfaction scale concerning obstetric care service). Most of the study sample (46%) were in age 26 – 30 years, and (26 %) were in the age group (20 – 25). years that 42% of the study sample were graduated from primary school, 38% were graduated from not writing and read and 14% were graduated from college and institution that most of the items with a high mean score in satisfying related to ward services and that the majority of items had an increased mean score in satisfying general services. The highest percentage of the study samples forty-six percent in age young group, we're living in the rural study sample were graduated from primary school, Findings demonstrated that the majority of items had high mean scores in satisfying related to delivery services also the majority of the women were found to be highly satisfied with the services received in maternity. The study's researcher advises enhancing nurses' practice when doing procedures by enrolling them in training courses. Increase the number of nurses working in hospitals to provide equal care for all hospitalized women and to reduce the likelihood of complications. Insist on the necessity of the Ministry of Health imposing sanctions against the nurse in the event that she accepts payment or employs abusive language.
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Association between medication adherence of oral corticosteroid based on MMAS-8 Score and SLEDAI Score in SLE children
Journal ID : AMJ-21-12-2022-10946; Author : Dedi Irwanto, Rita Evalina, Yunnie Trisnawati, Rina Amelia, Melda Deliana, Ika Citra Dewi Tanjung,
Abstract : Childhood-onset SLE is characterized by periods of flares and remissions. The SLEDAI score is one of the systems used to assess SLE activity. Long-term use of high-dose corticosteroids is associated with an increased risk of infection, metabolic and musculoskeletal diseases. This condition can cause non-adherence to taking medication in SLE patients. Medication adherence was assessed using the MMAS-8 Questionnaire. The study is to determine the association between medication adherence of oral corticosteroids based on MMAS-8 score with SLEDAI scores in SLE children at H. Adam Malik Hospital Medan. A retrospective observational study on 21 SLE children at Haji Adam Malik Hospital Medan who had received corticosteroid treatment for at least 3 months from May to July 2022. SLEDAI scores and adherence to corticosteroid medication were assessed using the MMAS-8 questionnaire. 21 samples were assessed for SLEDAI scores and adherence to taking corticosteroid medications using the MMAS-8 questionnaire. Most of the subjects showed a high level of compliance amounting to 9 people (42.9%). Kruskal Wallis test showed that there was a significant relationship between the level of treatment adherence and SLE disease activity at control time (p = 0.002). The Wilcoxon test showed that there was no difference in the mean score of SLEDAI between before and after treatment (p = 0.057). There is a relationship between medication adherence of oral corticosteroids based on MMAS-8 score with SLEDAI scores in SLE children at H. Adam Malik Hospital Medan.
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