This study aimed to evaluate the impact of simulation as a teaching tool for the technique of the cervical-uterine smear and the announcement of the results as part of the training of 5th year students of medicine at the Faculty of Medicine and Pharmacy of Agadir (FMPA). This is a monocentric cross-sectional descriptive study. Seven sessions were held, and each session consisted of a practical workshop and two simulation sessions. Two questionnaires were used to collect the data. They focused on the evaluation of knowledge (pre-test), then the evaluation of the knowledge and skills acquired (post test) of the students. Ninety-two students participated in this training. The results showed that 78% of the learners had an improvement in their level of knowledge (p=.00001) after the session. 95% expressed apprehension before taking a cervical smear compared to 3% at the end of the session (p=0.000). In addition, learners expressed difficulties in communicating with patients, especially in the non-verbal aspect, with a significant improvement (48% at the beginning of the session vs. 16% at the end of the session (p=.00001)). Finally, all learners were willing to attend another simulation training session. This study has shown that simulation training for Pap smear and announcement consultation leads to a significant improvement in the knowledge and skills of the learners. To improve patient care, simulation-based training for Pap smear should be included in the curriculum for students as well as sessions of certified training for practicing physicians.