Understanding of COVID-19 is still evolving, and COVID-19 statistics are dynamic. The purpose of this study was to use COVID-19 data to examine the spread of COVID-19 in the continent of Africa by the end of September 2022 and compare it to the global spread. Online data on COVID-19 statistics were extracted from the "Worldometer" website. As of October 1, 2022, Africa has recorded 12,647,710 confirmed cases of COVID-19 (2% of all cases worldwide) and 257,630 deaths (3.9%). Of the 6.7 billion tests performed, only 1.6% were in Africa. Moreover, COVID-19 statistics have not been consistent across the continent; half of the deaths occurred in two countries: Tunisia and South Africa. The median age was significantly proportional to the number of deaths per million and the number of tests in Africa but the correlation test was not significant among European countries. Globally, the number of cases/deaths was proportional to the number of tests. Unlike the initial predictions, the severity of the pandemic of COVID-19 has remained low in Africa. The definition of suspected cases, testing strategies, and the criteria for when a result is considered positive is not universally standardized, as well as the difference in the capacity to perform testing between countries. All of these make big differences in COVID-19 statistics around the world and over time. Thus, in the event of an epidemic or outbreak, the efforts of public authorities must focus on protecting the most vulnerable groups, especially the elderly living in nursing homes.