Abstract : TORCH (Toxoplasmosis, Rubella, Cytomegalovirus, and Herpes Simplex) infections are diagnosed by examining the blood for the presence of antibodies of the IgM, and IgG classes to the pathogens of toxoplasmosis, rubella, cytomegalovirus, and herpes. Determine the concentration of antibodies to the listed pathogens. If there are antibodies, this does not mean that the person is necessarily sick. This may mean that he once had this infection and is immune to it. However, if the number of antibodies to a particular infection is very high or increases over time, this already indicates the activity of the process. Moreover, clinically, the disease may not manifest itself or manifest itself in dim, erased forms. The severity of the external manifestations of the disease is in no way connected with the danger of its impact on the fetus. With a pronounced disease, the fetus can remain healthy, and, conversely, in the absence of clinical manifestations, the fetus may or may not be severely affected. Antibodies of Class IgM in the blood appear 2-4 weeks after infection and disappear after 3-9 months. By 3-4 weeks, antibodies of the IgG class appear, and their concentration gradually increases and reaches a peak by 2-5 months from infection. Antibodies of the IgG class remain in the blood for a long time, sometimes for life. If a woman planning a pregnancy, as well as a pregnant woman up to 12 weeks of gestation, is found to have negative.