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Azerbaijan Medical Journal

(ISSN: 0005-2523)

Azerbaijan medical journal (ISSN: 0005-2523) - is a scopus indexed journal since 1961. The publisher of the journal is Izdatel'stvo Elm by WHO Office in Azerbaijan. Azerbaijan medical journal (AMJ) is also UGC approved. The journal publishes general medicine, health science, psychological, pharmaceutical journals and so on. Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Interventional Pulmonology Zhenkong Kexue yu Jishu Xuebao/Journal of Vacuum Science and Technology

Aim and Scope

Azerbaijan Medical Journal

Azerbaijan Medical Journal (ISSN: 0005-2523) - is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to. Zhongguo Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of China University of Petroleum (Edition of Natural Science) Tobacco Science and Technology Teikyo Medical Journal Connected Health Wuhan Ligong Daxue Xuebao (Jiaotong Kexue Yu Gongcheng Ban)/Journal of Wuhan University of Technology (Transportation Science and Engineering) Zhonghua yi shi za zhi (Beijing, China : 1980) Agricultural Mechanization in Asia, Africa and Latin America International Medical Journal Technology Reports of Kansai University Asia Life Sciences Open Access Journals Tagliche Praxis

Anatomy Physiology Biochemistry Pharmacology Pathology Forensic medicine Microbiology Community Medicine Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases Anaesthesia Cancer research Neurosurgery Orthopedics Gastroenterology Neurology Nephrology Medical education Orthopaedics Paediatrics Reproduction Cardiology Diabetes Surgery Nursing Otolaryngology Dental Psychology Anesthesiology Dermatology Endocrinology Hepatology Urology Venereology Psychiatry Biotechnology Pharmacy ENT Pharmaceutical Chemistry Pharmaceutical Analysis Pharmaceutics Pulmonology Pharmacognosy Pharmaceutical Phatmaceutical Technology Biopharmaceutics Pharmacokinetics Pharmacodynamics Industrial Pharmacy Drug Design Quality Assurance Drug Regulatory Affairs Phytochemistry Drug Delivery Systems Pharmaceutical Nanotechnology Pharmaceutical Microbiology Hospital Pharmacy Clinical Pharmacy Pharmacy Practice Drug Discovery Drug Metabolism Toxicology Clinical Research Pharmacogenomics Phrmacoinformatics Pharmacovigilance< Life Sciences like Chemistry Biomedical Sciences Microbiology Immunology Forensic Epidemiology Oncology Biomedicine Dentistry Physiotherapy Gynaecology Dermatoepidemiology Neuroscience Ophthalmology Sexology Osteology Kinesiology Angiology/Vascular Medicine Critical care Medicine Haematology Infectious Diseases and Vaccinology Bariatrics Pharmacy and Nursing Pharmacognosy and Phytochemistry Radiobiology Clinical immunology Clinical and Hospital Pharmacy Cell Biology Genomics and Proteomics Healthcare Services Healthcare Management Bioinformatics and Biotechnology Geriatric Medicine Bulletin of National Institute of Health Sciences Journal of the Austrian Society of Agricultural Economics Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Interventional Pulmonology Zhenkong Kexue yu Jishu Xuebao/Journal of Vacuum Science and Technology Wuhan Ligong Daxue Xuebao (Jiaotong Kexue Yu Gongcheng Ban)/Journal of Wuhan University of Technology (Transportation Science and Engineering) Zhonghua yi shi za zhi (Beijing, China : 1980) Zhongguo Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of China University of Petroleum (Edition of Natural Science) Tobacco Science and Technology Teikyo Medical Journal Connected Health

Latest Journals

Azerbaijan Medical Journal

Agricultural Mechanization in Asia, Africa and Latin America International Medical Journal Technology Reports of Kansai University Asia Life Sciences Open Access Journals Tagliche Praxis Bulletin of National Institute of Health Sciences Journal of the Austrian Society of Agricultural Economics
QUANTITATIVE ANALYSIS OF GENERIC CEFIXIME IN HEALTHY SUBJECTS USING UPLC-MS/MS AND ITS BIOAVAILABILITY AND PHARMACOKINETICS EVALUATION UTILIZATION
Journal ID : AMJ-06-11-2022-10723; Author : Yuli Subiakto, Haris Rismawan, Syahrul Tuba,
Abstract : This study aims to compare the bioavailability of Lafsefik Dry Syrup (Lafsefik DS) containing 100 mg/5 ml cefixime with Suprax Oral Suspension (Suprax OS). The bioequivalence test was carried out with a cross-sectional study design with two stages, a randomized, crossover, two-way, double-blind, single-dose control, with pharmacokinetic parameters including AUC 0-t, Cmax, Tmax T1/2, which included 21 male and female healthy adult individuals under fasting conditions. Blood plasma levels were measured using ultra-performance liquid chromatography-tandem mass spectrometry (UPLC–MS/MS). The comparative dissolution test of the Lafsefik DS test drug product was 28.82% at pH 1.2, 62.99% at pH 4.5, and 69.90% at pH 6.8, as indicated by the F2 value. The F2 value was <50% with Suprax OS at pH 1.2 and >50% at pH 4.5 and pH 6.8. The results of the bioequivalence test showed AUC0-32= 22.857±7.639 ng ml-1 hour, AUC0-inf = 23.440±7.720 ng mL-1.hour, Cmax = 2.695± 858 ng mL-1, Tmax= 4.05 ±0.79 hours, and T½= 3.98 ± 0.38 hours. The values of the Suprax OS were AUC0-32 = 21.496±5.849 ng mL-1.hour, AUC0-inf = 22.032±5.863 ng mL-1hour, Cmax = 2.561±554 ng mL-1, Tmax = 4.19 ±0.84 hours, and T½ = 4.02 ±0.51 hours. The geometric mean ratio of test drug to innovator drug (90% CI) showed bioequivalence with values of AUC0-32= 104.71% (98.13-111.23), Cmax= 102.61% (95.79-109.61), CV intrasubject of AUC0-32= 11.70%, and Cmax = 11.31%. The Lafsefik DS test drug product shows a similarity of an F2 value >50% and is bioequivalent.
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The durability of Temporary Hemodialysis Catheter by Insertion Site in Hemodialysis Patients in Dr. Soetomo Hospital Surabaya
Journal ID : AMJ-06-11-2022-10722; Author : Edi Surya Bara, Heroe Soebroto, Dhihintia Jiwangga,
Abstract : Temporary hemodialysis catheter (NTHC, Non-tunneled hemodialysis catheter) can be used in cases of Acute Kidney Injury (AKI) and Chronic Kidney Disease (CKD) in emergency settings. According to KDOQI 2019 guidelines, NTHC should not exceed two weeks in Internal Jugular or Subclavian vein and five days in the femoral vein. However, the use of NTHC in Indonesia and many other countries exceed the recommended use. This study aims to determine the durability of NTHC on three different sites (Internal Jugular, Subclavian, and Femoral Vein) and determine factors influencing the durability of NTHC. This prospective cohort observational analytic study used a consecutive sampling method to recruit subjects that meet inclusion and exclusion criteria. Every subject was then followed until the occurrence of an event. Data censoring was applied for the elective removal of the NTHC. Of the 74 subjects, the durability NTHC in Internal Jugular, Subclavian and Femoral veins were 36.29, 46.91, and 33.00 days respectively. By statistics, no significant differences were observed. However, multivariate analysis showed that the risk of the event was four times higher in the femoral vein site. The most extended catheter durability was the subclavian vein, with the femoral vein showing the highest risk.
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Echocardiographic Evaluation of Patients with Rheumatoid Arthritis
Journal ID : AMJ-06-11-2022-10721; Author : Dr.Jasim Mohammed Tayeb, Rafal Tariq Saeed Al-Fee,
Abstract : Rheumatoid arthritis (RA) is a chronic inflammatory disease of the joints that may also manifest with extra-articular characteristics. Cardiovascular disorders are among those extra-articular characteristics, including pericarditis, cardiomyopathy, myocarditis, cardiac amyloidosis, coronary vasculitis, arrhythmia, valve diseases, and, most significantly, congestive heart failure and ischemic heart disease. RA is linked to a higher death rate when compared to the general population, the bulk of which is caused by cardiovascular illnesses. The aim of this study is to assess the prevalence of Echocardiographic findings in patients with an established diagnosis of rheumatoid arthritis. A total of 50 patients (42 female: 8 male) diagnosed to have RA according to the ACR/EULAR classification criteria for Rheumatoid arthritis were involved in this cross-sectional study. Data collection was done using questionnaires and interview. Age, gender, disease duration, current medications, rheumatoid factor, anti CCP and Hemoglobin concentration. All subjects were evaluated by Trans-thoracic Echocardiography to determine cardiac functional and structural abnormalities. Mean age for patients was 49.53± 11.55 years. Echocardiographic abnormalities were found in 26 (52%). Most common echocardiographic abnormality was diastolic dysfunction. This study shows significant prevalence of cardiac involvement in RA patients.
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Relationship between Troponin Level and Systolic and Diastolic Dysfunction in Children with Sepsis
Journal ID : AMJ-06-11-2022-10720; Author : Jessica Esmeralda Ginting, Munar Lubis, Karina Sugih Arto,
Abstract : Sepsis induced myocardial dysfunction (SIMD) increases mortality risk to 70-90% compared to sepsis without cardiovascular system dysfunction. Troponin is a specific and sensitive marker for myocardial injuries, where high troponin levels are frequently reported in critically ill adult patients. However, very few studies are available on systolic and diastolic heart functions in child patients with sepsis in relation to troponin levels. This was a prospective cohort research to assess the troponin levels and the relationship with systolic and diastolic dysfunction at 24 and 72 hours of pediatric sepsis at the PICU in Haji Adam Malik and Universitas Sumatera Utara hospitals Medan, Indonesia. The relationship between the mentioned variables was assessed using paired t-test for normal distribution or Mann-Whitney test for non-normal distribution data. Research subjects were children aged between 1 month to 18 years old that fulfilled sepsis criteria according to PELOD-2 scoring system. Patients with congenital heart diseases and myocarditis, as well as post-heart surgery patients were not included in the study. The frequency distribution of systolic and diastolic function showed no systolic dysfunction in patients. However, diastolic function assessment showed 8 patients (26.7%) with diastolic dysfunction on the first day of sepsis diagnosis, and the number increased to 11 patients (36.7%) on the third day of sepsis diagnosis. Troponin I and T showed a significant relationship with diastolic dysfunction (p<0.05). Troponin T and troponin I values measured on the first 24 and 72 hours of sepsis diagnosis or PICU treatment can indicate diastolic dysfunction.
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Sunrise Syndrome: A Case Report
Journal ID : AMJ-05-11-2022-10718; Author : Delfi, Faiza Sofia Sari, Barii Hafidh Pramono,
Abstract : Sunrise syndrome is a complication that most often occurs after cataract surgery. This complication occurs in cataract surgery with improper fixation of the IOL inside the capsular bag, or incomplete capsulorhexis. Overall, the incidence rate of Sunrise syndrome has actually decreased a lot with the increasing use of curved capsulorhexis and phacoemulsification with the safe placement of IOL in capsular bag [1]. To report the case of a patient who had sunrise syndrome. Woman 52 years old with main complaint blurry vision in both eyes since 3 months ago. Visual acuity examination revealed the visual acuity of Hand movement on the right eye. There was no improvement with pinhole, and the vision of the left eye was 0.20 with a pinhole of 0.40. Intraocular pressure in the right eye was 17 mmHg. The anterior segment was within normal limits, except the lens appeared cloudy. The patient was diagnosed with mature senile cataract on her right eye and underwent cataract extraction with the phacoemulsification method. Postoperative visual acuity phacoemulsification H+7 the patient complained of glare sometimes like seeing a rainbow, and occasional double vision in the eye that had been operated on. On visual acuity examination, the vision was 0.17, and there was a shift in the IOL lens. In patients with sunrise syndrome, treatment with the capsular tension ring (CTR) approach is quite effective, with the result IOL in a central position and visual progress.
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Effects of Training of Rice Farmers in OHS and Use of PPE on The Occurrence of Occupational Accidents and Rice Production
Journal ID : AMJ-04-11-2022-10717; Author : Anderias Umbu Roga, Lientje Setyawati, Frans Umbu Datta, Adi Heru Sutomo,
Abstract : Accidents among rice farmers are on the rise. We conducted a two year quasi experiment to investigate the effects of training on occupational health and safety standards (OHS) and use of personal protective equipment (PPE) on the occurrence of occupational accidents (OA) and rice production by rice farmers in rural Java Island, Indonesia. We randomly chose 70 rice farmers from adjacent villages within one sub-district of Sleman Regency. These farmers were randomly allotted to two groups of thirty-five people; both groups were given PPE since the first year, later on the second year, only group one were trained on OHS and use of PPE while the other group (C) were left untrained. We used descriptive analyses for use of PPE and an independent t-test was used to analyse variables, including cases of OA, age of farmers, education level and rice production. The results show that both OHS and the use of PPE enabled group T to have significantly (P<0.01) lower cases of OA than that of the control group C(1.57 vs. 2.38), leading to longer productive time to farm for the former group. Interventions on group T effectively (P<0.05) reduced risks of accidents or illness during rice farming by 75%. Group T produced much more (P<0.001) rice than group C (7,32 vs. 3,71; tonnes/ha); possibly because group T had a longer productive time. OHS training and use of PPE significantly reduced risks of OA and increased rice production.
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KNOWLEDGE ABOUT CERVICAL CANCER AMONG URBAN AND RURAL WOMEN IN THE EAST COAST OF MALAYSIA
Journal ID : AMJ-04-11-2022-10716; Author : zuraida anuar, zakira mamat, tengku alina,
Abstract : Cervical cancer is the third leading cause of death among at-risk reproductive women in Malaysia. This study was to find out the level of knowledge about cervical cancer among urban and rural women. The study involved women aged between 30 and 65 years. The design of this comparative study was conducted to compare the level of cervical cancer knowledge among urban and rural women. The sampling method uses a probability sampling method based on sampling criteria and sample exclusion criteria. The IBM Corp.'s 2013 Statistical Package for Social Sciences (SPSS) version 20 software was used to analyse the data in this study. The results show that the percentage of this knowledge is good for urban and rural women on the east coast of Malaysia.
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Clinical Approach in Generalized Pustular Psoriasis : One Case Report
Journal ID : AMJ-03-11-2022-10715; Author : Siti Nur Rahmah, Irma Helina, Wiwiek Dewiyanti Habar, Suci Budhiani, Faridha Ilyas, Ketut Alit Pinidha Savitri,
Abstract : Generalized pustular psoriasis (PPG) is a rare subtype variation of pustular psoriasis. No specific therapeutic agent for PPG has been approved in the United States and Europe yet. Standard guidelines for PPG therapy do not yet exist, so therapy is determined based on the clinical. A case is reported, a 22-year-old woman with complaints of purulent papules on almost the entire body for 1 week ago. The patient had a history of red scaly patches for 3 years ago. On generalized regional dermatological status, diffuse miliary pustules were found on an erythematous basis with desquamation. Histopathological results showed subcorneal pustules with segmented (spongiform) neutrophil inflammatory cells infiltration. The patient was diagnosed as PPG and treated with methotrexate 7.5 mg/week. The patient showed significant lesion improvement within 14 days of treatment.
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Knowledge of Safe Handling of Chemotherapy among the nurses in Queen Elizabeth Hospital, Kota Kinabalu, Sabah
Journal ID : AMJ-03-11-2022-10714; Author : Patricia Sator, Adeline Yip Get Yee, Walton Wider,
Abstract : There are various types of cytotoxic agents used in the treatment of chemotherapy, and each agent can cause undesirable side effects in both patients and nurses, who are also skilled in dealing with these antineoplastic agents. Twenty true or false, closed-ended questionnaires were utilised to assess and evaluate the knowledge of nurses regarding the safety of chemotherapy. A total of 107 nurses participated in the assessment and evaluation, with only 59.22% receiving correct answers overall. The majority of respondents, 73.8% (79 out of 107) demonstrated moderate knowledge with 10 to 16 correct responses out of 20 questions. The majority of their knowledge regarding the safe handling of chemotherapy came from Continuous Nursing/Medical Education (CNE/CME) and the internet respectively. In general, the results demonstrated that nurses have insufficient knowledge of cytotoxic agents, as evidenced by the fact that the average percentage of correct responses was below 60%. Therefore, nurses must receive extensive additional education about anticancer agents in nursing school and through in-hospital continuing education. It is essential for nurses to participate in a structured educational programme, such as a Post Basic or Advanced Diploma in Oncology Care, in order to obtain proper updates and certification. In addition, the study suggested that updating the knowledge of safe handling among nurses with supported guidelines and policies will aid in enforcing safety implementation within clinical settings.
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Changes In Clean Living Behavior In Mentally Retarded Children: An Quasi-Experimental Study Using The Flashcard Method
Journal ID : AMJ-03-11-2022-10713; Author : Arfah Husna, Arfah Husna,
Abstract : Children with mental retardation have a high vulnerability to exposure to diseases such as Covid-19. Special interventions are needed to increase the knowledge of mentally retarded children so that they can practice handwashing skills with soap so as to minimize the transmission of Covid-19 and other diseases. One method that can be applied in the intervention of handwashing with soap is the drill method with flashcard media. This study aims to examine the effect of the flashcard-based drill method intervention on increasing the ability of mentally retarded children to wash their hands with soap. This study uses a Quasi-Experimental design. The planned design is a one group before and after intervention design. Based on the results of the bivariate test, it is known that there is a significant effect of flashcard-based drill method education on improving hand washing skills with soap in mentally retarded children, Samatiga District, West Aceh Regency. Research clearly shows that the flashcard-mediated drill method intervention has an effect on increasing the knowledge of mentally retarded children so that they are able to practice hand washing behavior with soap so as to minimize the risk of contracting Covid-19 and other bacteria.
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