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Azerbaijan Medical Journal

(ISSN: 0005-2523)

Azerbaijan medical journal (ISSN: 0005-2523) - is a scopus indexed journal since 1961. The publisher of the journal is Izdatel'stvo Elm by WHO Office in Azerbaijan. Azerbaijan medical journal (AMJ) is also UGC approved. The journal publishes general medicine, health science, psychological, pharmaceutical journals and so on.

Aim and Scope

Azerbaijan Medical Journal

Azerbaijan Medical Journal (ISSN: 0005-2523) - is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to.

Anatomy Physiology Biochemistry Pharmacology Pathology Forensic medicine Microbiology Community Medicine Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases Anaesthesia Cancer research Neurosurgery Orthopedics Gastroenterology Neurology Nephrology Medical education Orthopaedics Paediatrics Reproduction Cardiology Diabetes Surgery Nursing Otolaryngology Dental Psychology Anesthesiology Dermatology Endocrinology Hepatology Urology Venereology Psychiatry Biotechnology Pharmacy ENT Pharmaceutical Chemistry Pharmaceutical Analysis Pharmaceutics Pulmonology Pharmacognosy Pharmaceutical Phatmaceutical Technology Biopharmaceutics Pharmacokinetics Pharmacodynamics Industrial Pharmacy Drug Design Quality Assurance Drug Regulatory Affairs Phytochemistry Drug Delivery Systems Pharmaceutical Nanotechnology Pharmaceutical Microbiology Hospital Pharmacy Clinical Pharmacy Pharmacy Practice Drug Discovery Drug Metabolism Toxicology Clinical Research Pharmacogenomics Phrmacoinformatics Pharmacovigilance< Life Sciences like Chemistry Biomedical Sciences Microbiology Immunology Forensic Epidemiology Oncology Biomedicine Dentistry Physiotherapy Gynaecology Dermatoepidemiology Neuroscience Ophthalmology Sexology Osteology Kinesiology Angiology/Vascular Medicine Critical care Medicine Haematology Infectious Diseases and Vaccinology Bariatrics Pharmacy and Nursing Pharmacognosy and Phytochemistry Radiobiology Clinical immunology Clinical and Hospital Pharmacy Cell Biology Genomics and Proteomics Healthcare Services Healthcare Management Bioinformatics and Biotechnology Geriatric Medicine

Latest Journals

Azerbaijan Medical Journal

A case series of Mucormycosis during Covid-19 Pandemic in a tertiary care hospital
Journal ID : AMJ-24-08-2022-10471; Author : Dr Ravish kumar M, Dr Nagarkar Rajhans, Dr Praveen kumar Doddamani, Dr Dinesh valse, Dr Parandekar Prashant, Dr Prathiba lokesh,
Abstract : Rhino-orbital Mucormycosis is an opportunistic fungal infection affecting mainly diabetic and other immunocompromised patients. Covid-19 infection has augmented the risk of mucormycosis cases due to use of steroids or due to immunosuppressed condition because of infection itself. In the present study four cases with rhino-orbital mucormycosis have been presented. They were etiologically diagnosed as Mucorales by KOH mount and fungal culture. Though diabetes and other immunosuppressed condition are at risk of acquiring Mucormycosis, In the present study 2 cases were not diabetic and didn’t had any immunosuppressive condition nor they were treated with steroids for covid-19 treatment. Hence we suggest that mucormycosis could be suspected in immunocompetent individuals also.
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Indices of Renal impairment in patients with Atrial Fibrillation
Journal ID : AMJ-24-08-2022-10470; Author : Rusul Mahdi Abid, Rusul Mahdi Abid, Rusul Mahdi Abid,
Abstract : Atrial fibrillation is the commonest type of arrhythmias with significant mortality and morbidities. There is a correlation between AF and renal impairment and this correlation is complex and may be a manifestation of cardiorenal syndrome, a bidirectional complication of these diseases or its treatment or both coexist in same disease. To evaluate frequency of renal indices abnormality among patients with atrial fibrillation. By using cross sectional descriptive study, randomly selected 52 atrial fibrillation patients admitted to Coronary care unit in Al-Nasiriya city underwent a complete evaluation for renal indices including blood urea, serum creatinine, urinalysis, serum electrolytes, Albumin creatinine ratio and ultrasound for renal system. Also performed questionnaire were obtained from all patients. Patients labeled as chronic kidney disease or underwent to renal replacement therapy were excluded. Mean age of patient’s 59.6±13.1 years and for Age at diagnosis 56.9±14.9. All patients have one or more abnormal renal indices. Most abnormalities appear in urinalysis (100% of patients) followed by abnormal Albumin creatinine ratio (48% of patients), Blood urea in 26.92%, Serum creatinine in 9.6% and ultrasound in 7.69%. 75% had chronic diseases plus AF. Significant correlation between male gender and highly abnormal blood urea (P.value=0.05), serum creatinine (P.value=0.014) and Albumin creatinine ratio (P.value=0.013). Also between direct cardioversion shock and blood urea (P.value=0.018), serum creatinine (P.value=0.006) and Albumin creatinine ratio (P.value=0.047). Blood urea correlated with abnormal echo finding (P.value=0.02) and number of medications that used for atrial fibrillation management (P.value=0.031). Some renal indices is abnormal in Atrial fibrillation patients especially urinalysis, blood urea, serum creatinine and Albumin creatinine ratio. In addition, this abnormality related to gender, using of direct cardioversion shock, echo abnormalities and number of medications for atrial fibrillation.
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Functional Capacity Changes After Cardiac Rehabilitation Program as A Quality of Life Predictor in Left Ventricular Dysfunction Patients Who Underwent Coronary Artery Bypass Grafting
Journal ID : AMJ-24-08-2022-10469; Author : Cut Aryfa Andra, Hery Diansyah Putra, Abdul Halim Raynaldo, Yuke Sarastri, Rusdiana Rusdiana,
Abstract : For Patients with coronary artery disease (CAD) accompanied by decreased left ventricular ejection fraction (LVEF), coronary artery bypass grafting (CABG) was the preferred management and superior to pharmacological therapy alone. Health assessment related to the quality of life in patients with CAD and post-CABG is important and intended for evaluating the acquisition of the therapeutic target. Based on the guidelines, treatments of CAD should be accompanied by lifestyle modification and cardiac rehabilitation. The aim of the study was to assess functional capacity changes (∆METs) after phase II cardiac rehabilitation as a predictor of quality of life 3 months after CABG. A cohort study methods on patients with LV systolic dysfunction who underwent CABG between January 2019 and January 2021. Patients were submitted to phase II cardiac rehabilitation, where ∆METs showed changes in functional capacity before and after the program. The abnormality of ∆METs as a predictor was determined by the cut-off point using ROC and AUC curve in the previous study which was 3.25 METs.5 Observe-component was patients’ quality of life 3 months after CABG using Kansas City Cardiomyopathy Questionnaire (KCCQ). The study showed there was a significant relation between ∆METs and KCCQ scores with moderate strength (p<0.01; r = 0.592), and showed the lower ∆METs group had a 5.3 times greater risk of poor quality of life than the higher ∆METs group 3 months after CABG (p<0.01; OR = 5.3). The conclusion of the study showed that Functional capacity changes after phase II cardiac rehabilitation could predict the quality of life after CABG in patients with LV systolic dysfunction by using KCCQ.
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Detection of Extended-spectrum β-lactamases Genes in the Zoonotic Brucella abortus
Journal ID : AMJ-23-08-2022-10468; Author : 1Ali Nayyef Umayra, Jabbar S. Hassan, Rand R. Hafidh, Thanaa R. Abdulrahman,
Abstract : Brucellosis is a frequent infectious zoonosis over the world, intimidating both veterinary and human public health. The misuse and overuse of antibiotics in Iraq in the veterinary field is associated with the high rate of antibiotic resistance that observed in some zoonotic bacteria directing to cause serious infections in human. The point of this study; is to determine the occurrence of extended-spectrum beta-lactamases (ESBLs) -producing Brucella abortus in the blood of cattle. One hundred blood samples were obtained from cattle in a number of slaughterhouses in different areas of Baghdad. Equal to 10 ml of blood samples were collected from the tail vein of the animals. Blood was divided into two parts; the first part (7ml) in Trypticase soy broth, incubated at 37 °C with 5–10% CO2 for 2-3 days. Later, Bacterial DNA was extracted and a specific set of primers were used for the detection of β-lactamases genes in Brucella abortus isolated using multiplex-PCR technique. of 100 blood samples used in this study 26 isolates (26%) were confirmed to be Brucella abortus species by VITEK-2 System. The ESBLs genes; blaTEM gene was detected in 9 of 26 (34.6%) isolates, followed by blaCTX-M gene in 7(26.9%) isolates, blaAMPC gene in 6 (23.0%) isolates, and blaSHV gene in 4 (15.3%) isolates. This study indicated the high rate of ESBLs- producer Brucella abortus among cattle. Thus, indicating the potential of animals as a source of the ESBLs-producer bacteria that transmitted to human via the food chain or other recreational activities.
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The Effect of an Animation Video on Pain Response of 3-6 Years Old during Injection Intravenous
Journal ID : AMJ-23-08-2022-10467; Author : Islaeli Islaeli, Faridah Mohd Said, Nisha Nambiar,
Abstract : Animated videos are one of the easiest ways to play when the child receives a medicine injection via an intravenous catheter that might reduce pain response. This study aimed to determine the effect of animation video on pain response for 3-6 years old during injection medicine via intravenous catheters. The study employed a quasi-experimental pre-test - post-test design. The intervention group (n: 107) was provided with an animation video during intravenous therapy, and the control group (n: 106) received standard care. FLACC (r: 0.845) was used to measure behavioural pain response, while heart rate was used to assess physiological pain response. Animation video with content validity index (Aiken’s V: 0.86). There were statistically significant differences in pain response, behavioral pain response, and physiological pain response between the intervention group and the control group. Animation video intervention can be used to reduce procedural pain during injection medicine intravenous therapy.
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Evaluation of the locally applied doxycycline on alveolar osteitis incidence following surgical removal of impacted mandibular third molars
Journal ID : AMJ-23-08-2022-10466; Author : Rasheed Musleh Ibrahem, Assist. Prof. Dr. Ali H. Abbas Al Hussaini,
Abstract : One of the most common oral procedures carried out every day in oral and maxillofacial surgery units is the surgical removal of impacted mandibular third molars. After the impacted mandibular third molar has been removed, postoperative morbidity is unavoidable. Alveolar osteitis, a painful, unhealed socket, is one of the most frequent surgical sequelae. By introducing and applying a new material inside the extraction socket, many researches were attempted to prevent the development of alveolar osteitis. This study aims to make a comparison between the effect of the locally applied Doxycycline and the systemic Doxycycline on the occurrence of alveolar osteitis after surgical removal of impacted mandibular third molars. A randomized prospective clinical study was conducted on 50 patients who had undergone surgical removal of impacted mandibular third molars under local anesthesia. The patients were distributed in 2 groups: Study group; included 25 patients treated by local application of Doxycycline inside the socket immediately after surgical removal of impacted tooth. Control group: consisted of 25 patients who received systemic Doxycycline one hour before surgical removal of impacted tooth. Alveolar osteitis was evaluated on the 2nd and 7th day after surgery. There was a significant reduction of alveolar osteitis in the study group in comparison to the control group (p< 0.05). The local application of Doxycycline significantly reduces the incidence of alveolar osteitis.
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Effectiveness of locally applied clindamycin on the occurrence of alveolar osteitis following surgical removal of impacted mandibular third molars. A comparative study
Journal ID : AMJ-23-08-2022-10465; Author : Dashti Ali Mohammed, Assist. Prof. Dr. Ali H. Abbas Al Hussaini,
Abstract : One of the most frequent procedures in oral surgery units is the removal of a partially or completely impacted mandibular third molar under local anesthesia and it directly affects the patient's quality of life. The aim of this study is to make a comparison between the effect of the locally applied clindamycin and the systemic clindamycin on occurrence of postoperative alveolar osteitis following surgical removal of impacted mandibular third molars. Fifty patients who had undergone the surgical removal of an impacted mandibular third molar under local anesthesia participated in a randomized prospective clinical study. The patients were distributed in 2 groups. Study group included 25 patients treated with local application of clindamycin inserted inside the socket after surgical removal of impacted tooth, while control group comprised of 25 patients treated with systemic clindamycin one hour before surgical removal of the impacted tooth. The occurrence of alveolar osteitis was evaluated on the 2nd and 7th day postoperatively. Alveolar osteitis occurred on the 48 hours postoperatively. The total incidence of alveolar osteitis was 10%. The incidence of alveolar osteitis was more in control group (16%) when compared to study group (4%) and the difference was statistically significant. Local application of saturated gelfoam by clindamycin reduces the incidence of alveolar osteitis to a significant level when compared to systemic clindamycin.
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Association between BsmI (rs1544410) and TaqI (rs731236) VDR Gene Polymorphisms with Vitamin D Status in Type 2 Diabetes Mellitus Patients
Journal ID : AMJ-22-08-2022-10464; Author : Sufitni Sufitni, T. Helvi Mardiani, Yunita Sari Pane, Siti Syarifah, Mutiara Indah Sari,
Abstract : Type 2 Diabetes Mellitus (T2DM) arises due to combination of modifiable and non-modifiable. One of the modifiable risk factors is vitamin D concentration, which is associated with the incidence of T2DM and mediated by the vitamin D receptor (VDR). The aim of this study is to see the association between BsmI (rs1544410) and TaqI (rs731236) VDR gene polymorphisms with vitamin D status in T2DM patients in the city of Medan, Indonesia. 76 T2DM patients were enrolled in this study. The vitamin D levels are analyzed with enzyme-linked immunosorbent assay (ELISA). Genotyping of BsmI (rs1544410) and TaqI (rs731236) VDR gene polymorphisms are done with Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP) technique. In this study, 72.4% of T2DM patients have insufficient and deficient vitamin D status (35.50% and 36.9% respectively). Fisher's exact analysis of the association between vitamin D status with BsmI (rs1544410) and TaqI (rs731236) VDR gene polymorphisms is at p > 0.05, respectively. This study shows that genotype Bsm1 and genotype Taq1 are not associated with vitamin D status in T2DM patients.
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Bitter Gourd (Momordica charantia L.) Affects the Pharmacokinetics Profile of Metformin in Rabbits’ Plasma
Journal ID : AMJ-22-08-2022-10463; Author : Asri Dwi Endah Dewi Pramesthi, Agung Endro Nugroho, Endang Lukitaningsih,
Abstract : The drug-herb combination between metformin and bitter gourd needs further study of the benefits and risks. This study aims to explore metformin in plasma samples using the HPLC method and its pharmacokinetic profiles affected by the bitter gourd. This experimental method study with a post-test randomized controlled group design. Healthy albino rabbits were divided into three groups (n=3). They were administered with bitter gourd juice 100% (4 ml/kg BW) and metformin (BM1), bitter gourd juice 50% (4 ml/kg BW), and metformin (BM2), and metformin 26 mg/kg (M). BM1 and BM2 were given bitter gourd juice for 14 days, and then a single dose of metformin was given to all groups on the 15th day before metformin pharmacokinetic parameters were measured. Blood samples were collected from marginal ear vein punctures at 0, 10, 30, 60, 120, 240, 360, and 480 minutes. The plasma was analyzed using HPLC methods, and the concentration vs. time was used for a 1-compartmental open model pharmacokinetics analysis. Bitter gourd juice with 100% (4 ml/kg BW) concentration decreased the V/F and CL/F, also increased Ka, T1/2, Cmax, MRT, and AUC0-inf, also significantly increased AUC0-480, and decreased Tmax (p < 0.05). The pharmacokinetic interaction of metformin and Momordica charantia L. is presumably because of the competitive interaction between phytochemical constituents of bitter gourd and metformin on the OCT and MATE transporter.
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The Effectiveness of Education on Farmer Knowledge and Behaviors towards COVID-19 Prevention: A Study in an Agricultural Area
Journal ID : AMJ-22-08-2022-10462; Author : Yarmaliza, Teungku Nih Farisni, Fitriani, Zakiyuddin, Fitrah Reynaldi, Veni Nella Syahputri, Andi Imam Arundhana,
Abstract : Following the healthcare and sanitation protocol has been widely used to prevent COVID-19 transmission. The research objective was to determine the effectiveness of WASH educational collaboration on farmers as an attempt to COVID-19 prevention. This study was an observational pre-experimental pretest-posttest design study without a control group. This research was carried out in March 2021, located in two districts with high COVID-19 positive cases, Johan Pahlawan and Meureubo Districts, West Aceh, Indonesia. A total of 37 farmers were recruited as the study participants. Data were analysed using logistic regression. The study result shows a significant influence between the collaboration of WASH education on farmers to prevent COVID-19. The statistical test was significant at a p-value <0.05. Collaboration on WASH education for farmers is very influential in preventing COVID-19. It is believed that cross-sectoral involvement and roles can be maintained so that COVID 19 prevention behaviours through WASH can continue to be applied. Educative collaboration of WASH impacts the alteration of the behaviour toward farmers who live in the area confirmed to be infected by COVID 19.
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