Scopus Indexed

Scopus Indexed Journal & Country Rank

Ores

ores
Submission Deadline
Volume - 63 , Issue 02
30 Jan 2023
Day
Hour
Min
Sec
Submit Now
Upcoming Publication
Volume - 63 , Issue 01
31 Jan 2023

Azerbaijan Medical Journal

(ISSN: 0005-2523)

Azerbaijan medical journal (ISSN: 0005-2523) - is a scopus indexed journal since 1961. The publisher of the journal is Izdatel'stvo Elm by WHO Office in Azerbaijan. Azerbaijan medical journal (AMJ) is also UGC approved. The journal publishes general medicine, health science, psychological, pharmaceutical journals and so on.

Aim and Scope

Azerbaijan Medical Journal

Azerbaijan Medical Journal (ISSN: 0005-2523) - is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to.

Anatomy Physiology Biochemistry Pharmacology Pathology Forensic medicine Microbiology Community Medicine Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases Anaesthesia Cancer research Neurosurgery Orthopedics Gastroenterology Neurology Nephrology Medical education Orthopaedics Paediatrics Reproduction Cardiology Diabetes Surgery Nursing Otolaryngology Dental Psychology Anesthesiology Dermatology Endocrinology Hepatology Urology Venereology Psychiatry Biotechnology Pharmacy ENT Pharmaceutical Chemistry Pharmaceutical Analysis Pharmaceutics Pulmonology Pharmacognosy Pharmaceutical Phatmaceutical Technology Biopharmaceutics Pharmacokinetics Pharmacodynamics Industrial Pharmacy Drug Design Quality Assurance Drug Regulatory Affairs Phytochemistry Drug Delivery Systems Pharmaceutical Nanotechnology Pharmaceutical Microbiology Hospital Pharmacy Clinical Pharmacy Pharmacy Practice Drug Discovery Drug Metabolism Toxicology Clinical Research Pharmacogenomics Phrmacoinformatics Pharmacovigilance< Life Sciences like Chemistry Biomedical Sciences Microbiology Immunology Forensic Epidemiology Oncology Biomedicine Dentistry Physiotherapy Gynaecology Dermatoepidemiology Neuroscience Ophthalmology Sexology Osteology Kinesiology Angiology/Vascular Medicine Critical care Medicine Haematology Infectious Diseases and Vaccinology Bariatrics Pharmacy and Nursing Pharmacognosy and Phytochemistry Radiobiology Clinical immunology Clinical and Hospital Pharmacy Cell Biology Genomics and Proteomics Healthcare Services Healthcare Management Bioinformatics and Biotechnology Geriatric Medicine

Latest Journals

Azerbaijan Medical Journal

Biofilm formation and CTX-M gene expression in Escherichia coli
Journal ID : AMJ-16-08-2022-10432; Author : Sara H A Mohammed, Hadeel K Musafer, Layla A Said,
Abstract : The majority of common Escherichia coli species is related to humans and cause extra-intestinal infections. There is a link between majority of these infections and bacterial CTX-M. The present study was conducted to investigate the relationship between biofilm formation and CTX-M gene expression in clinical E. coli isolates. Thirty-five clinical isolates of E. coli were obtained from different clinical samples including urine, blood, wounds, and burns from four hospitals in Baghdad. Antibiotic susceptibility and biofilm formation tests were carried out. Polymerase chain reaction (PCR) and reverse transcriptase-PCR were used to detect and evaluate the expression of the CTX-M gene. The isolates were resistant to cephalosporins, aminoglycosides, and carbapenems with values of 94.3, 60, and 14.3%, respectively. There was a significant (p <0.01) relationship between biofilm formation and resistance to multiple antibiotics in the E. coli isolates. The PCR assay revealed that 94.3% of the isolates have the CTX-M gene, but no significant correlation between the biofilm values and the concentrations of the CTX-M gene expression. The findings of this study suggest that these antibiotics can be used in the empirical treatment of E. coli-caused infection-linked biofilm formation, and the antibiotic sensitivity pattern aids in antibiotic selection.
Read more →
Evaluation of the literature with a rare case. Can they really be important? Cervical Blue Nevus
Journal ID : AMJ-16-08-2022-10431; Author : Gulchin Babayeva, Yunus Emre Purut, Serap Koch,
Abstract : Blue nevi are a subset of melanocytic proliferations of embryonic neural crest origin containing cells similar to dendritic melanocyte precursors. Cervical Blue Nevi are benign pigmented melanocytic lesions that are rarely detected and usually seen in middle-aged women. It has various shapes such as dentridic, spindle-shaped, oval or polyhedral forms. Blue or blue-black macules or papules are common on the dorsal hands and feet, neck, and trunk [1]. Also, interestingly, in other places where melanocytes do not exist. It can also be found; in oral mucosa, sclera, uterine cervix, vagina, prostate, spermatic cord, pulmonary hilus, conjunctiva, maxillary sinus, mammary lymph nodes [1], [2]. In female genital tracts, it most commonly occurs in the uterine cervix. It is usually detected incidentally on microscopic examinations. Clinically, it can be seen as a blue-black spot on the posterior wall of the cervix. Various authors have described these lesions as <0.5 cm small and solitary blue-black macules on the endocervix. Here, we presented the histopathological features and differential diagnosis of a blue nevus detected in the pathology material after hysterectomy in a 43-year-old patient, on examples from the literature.
Read more →
Physiological and histological effects of orlistat drug on thyroid gland of male albino rats
Journal ID : AMJ-16-08-2022-10429; Author : ZAHRA MOUSSA KAMEL, ABBAS ABED SHARHAN Al-OWAIDY,
Abstract : Orlistat is medication used to treat obesity. This research aim investigation how of relationship between orlistat treatment use and thyroid hormone levels. Thyroid hormones of obese of male albino rat have been studied. In addition, little is understand about how losing weight changes thyroid operation. Thus, we researched more about the thyroid hormone status and potential effect of weight loss on thyroid hormones. We study of 32 male albino rat obese with mean age 12 weeks. The animal divide to four groups and all group included Of these 8 animals. The first group is control, second group (120 mg /kg / day), third group (180 mg /kg / day) and forth group (240 mg /kg /day) for 12 weeks of treatment. The results showed had significant decrease (P ≤ 0.05) T4 level in Group 3 (8.041± 0.016) and group 4 (1.400±0.972) compared with control 31.600±0.0258 ng /ml. and total T3 level in Group 3 and 4 significantly decrease P ≤ 0.05) 6.233 ± 0.145; 0.340±0.021 compared with control 12.641±0.203) ng /ml, (P ≤ 0.05); while TSH level in Group 3,4 (2.491± 0.485, 5.243±0.673) had significant increase (P ≤ 0.05) compared to those of control without orlistat drug 0.691±0.057 uIU/ml and other groups. Obesity condition may effect thyroid hormone levels. beyond lowering body weight, orlistat may have varied effects on thyroid hormone status.
Read more →
ASPECTS OF MICRONUTRIENT ON LEPROSY IMMUNOLOGY RESPONSE
Journal ID : AMJ-15-08-2022-10420; Author : Akbar Pratama, Widyawati Djamaluddin, Anni Adriani, Safruddin Amin, Dirmawati Kadir, Andi Nurhaerani Zainuddin,
Abstract : Leprosy is an infectious disease caused by the Mycobacterium leprae attacking the skin and nerves leading to deformities of the hands, feet, and face. Every year more than 200,000 new cases of leprosy are reported globally, with Indonesia as one of the largest contributor. Nutritional status, particularly micronutrients, have role in development of the disease and nutritional balance could reduce the risk of contracting disease. It is also known that decreased levels of antioxidants and immune modulating nutrients may contribute to increasing in oxidative stress and complications. Thus, further studies considering the action of antioxidants and immune-modulatory nutrients in M. leprae infected patients should be designed to elucidate the pathogenic mechanism and to support dietary supplementation as the treatment of leprosy.
Read more →
The effect of Antibiotic on Patients Diagnosed by Corona Pandemic and Ways for Removing them: Azithromycin as a Case Study
Journal ID : AMJ-14-08-2022-10418; Author : Israa Abdulqader Abdulwahab, Fatima Khudair Abbas, Saba Dawod Salman,
Abstract : Pharmaceutical materials are defined as chemical compounds used in the treatment, prevention and diagnosis of diseases, thus maintaining the physical and mental health of humans and animals alike. These pharmaceuticals, especially antibiotics, pose a threat to humans and the environment at the present time, as their increased use led to an increase in their concentrations in wastewater, which led to the emergence of a new environmental problem. Due to the conversion of Corona disease into a pandemic suffered by the whole world, the use of antibiotics has increased significantly, including the drug azithromycin. For this reason, it is certain that azithromycin concentrations have increased dramatically in domestic or hospital wastewater, which must be treated with maximum efficiency, to maintain public health and safety on the one hand, and to avoid the occurrence of more serious complications on the other hand. The current review article highlights treatment methods for one of the most important types of antibiotics used in the last two years, which is azithromycin.
Read more →
Detection of Galectin-3 in serum of Iraqi patients with thyroid cancer for early diagnosis
Journal ID : AMJ-14-08-2022-10415; Author : Fatima Falah Hassan, Wafaa Fadhil Hamad, Luma Yousif Mehdi,
Abstract : Thyroid cancer is one of the fastest increasing cancers in recent years, with a 14.51 percent annual growth. It has been demonstrated that there is a link between several biomarkers and thyroid cancer progression. The goal of this study was to look at Galectin-3 (Gal-3) and liver function test(LFT); (AST, ALT, ALP) values in thyroid cancer patients. In the current study, (A hundred and forty-five) participants were separated into three groups: Group1: (sixty malignant thyroid gland patients), Group2: (thirty-five benign thyroid gland patients), and Group3: (fifty healthy control individuals as a control group). From November 2021 to February 2022, the patients were treated at the AL-Amal oncology Hospital in Baghdad, Iraq. Serum Gal-3 levels and liver function tests were measured in the study groups. Was to detection the levels of Galectin-3 levels biomarker and liver function test (AST, ALT, ALP) in serum of patients with thyroid tumor (malignant and benign) and compared to healthy as control, and measure by using ELISA techniques. The results showed that Gal-3 and LFT are significant difference in patients with malignant thyroid gland differ significantly from those in the control and benign tumor groups at (P<0.01). In the current research, Serum Galectin-3 levels were statistically higher in individuals with cancerous nodules than in benign and healthy controls. Furthermore, when compared to benign and healthy controls, LFT levels in patients with malignant nodules are statistically significantly higher.
Read more →
Proinflammatory cytokines and insulin resistance in patients with end-stage renal disease
Journal ID : AMJ-13-08-2022-10413; Author : Abtisam F. Al-Shukri, Hussein K. Al-Hakeim, Abbas F. Almulla,
Abstract : End-stage renal disease (ESRD) is a permanent deterioration of kidney functions and a life-threatening condition without dialysis or transplantation. Diabetes mellitus may result in diabetic nephropathy, the main cause of ESRD. We aim to delineate the ability of vitamin D (VitD), Granulocyte-macrophage colony-stimulating factor (GM-CSF), and interleukin (IL)-10 in diagnosing ESRD patients and examine their impacts on insulin resistance. We employed 90 participants distributed as healthy control (n=33) and ESRD patients (n= 57). We measured serum levels of IL-10, GM-CSF, VitD, albumin, insulin, glucose, creatinine, blood urea, phosphate ion, and uric acid. We found significant differences between ESRD patients and healthy control in serum levels of VitD, IL-10 and GM-CSF. There are significant correlations between kidney biomarkers (creatinine, blood urea and phosphate ion) and VitD and IL-10 but no significant correlation with GM-CSF. VitD was significantly correlated with IL-10 and GM-CSF. Receiver operating curve (ROC) curve and AUC analysis showed that VitD (sensitivity = 81.8 %, specificity = 79.9%, concentration=9.239 ng/ml), IL-10 (sensitivity = 75.4 %, specificity = 75.8%, concentration=7.419 pg/ml) and GM-CSF (sensitivity = 66.7 %, specificity = 64.6%, concentration=121.011 pg/ml) were significant diagnostic biomarkers in ESRD patients. ESRD is accompanied by increased inflammatory markers, namely IL-10 and GM-CSF, along with decreased VitD. Altered levels of the latter biomarkers could be a diagnostic tool for ESRD.
Read more →
Lipoprotein (a) screening in young and middle aged patients presented with acute vascular ischemic events (myocardial infarction & cerebral stroke)
Journal ID : AMJ-13-08-2022-10412; Author : Mohamed Hassanin, Sherif Arafa, Tamer Belal, Farouk Radwan, Nader El-shahat,
Abstract : High lipoprotein(a) (Lp(a)) is consider as an independent risk factor for Acute vascular ischemic events (e.g.: Myocardial infarction (MI) and ischemic stroke). However, Prior data from other large, population-based cohort studies have been conflicting on coronary artery disease and ischemic stroke, with some studies linking elevated Lp(a) levels to a higher incidence of myocardial infarction and ischemic stroke whereas others have not found any association. Lp(a) had been measured for patients < 65 years of age presenting with myocardial infarction or ischemic stroke to cardiology and neurology departments in Mansoura University Hospitals, Dakahlia Governorate, Egypt, during the period from June 2020 to May 2022. Logistic regression model was used to determine the independent association of clinical characteristics with elevated Lp(a). A total of 103 patients were screened for Lp(a); 71.8 % males, mean age 50.7±7.9 years. Median Lp(a) levels were 26.3 mg/dl (interquartile range [IQR] 2-74). Elevated Lp(a) > 30 mg/dL was observed in 41.7% and associated with younger age with acute vascular ischemic events specially MI (48%). In a multiple logistic regression model, Family history of premature AVSE (MI & ischemic stroke) (odds ratio [OR] 3.36, 95% confidence interval [CI] 1.3-8.6, p = 0.01), younger age (< 45years) (p = 0.048) were independently associated with elevated Lp(a) in all cases of AVSE, in MI cases Family history of premature of CAD was more significant associated with high levels of Lp(a) (odds ratio [OR] 20.4, 95% confidence interval [CI] 2.3-174, p = 0.001), younger age (p=0.016). In contrast, Lp(a) levels were not associated with other traditional cardiovascular risk factors in all cases of MI as a subgroup. Young and middle aged patients < 65y years presented with acute vascular ischemic event (MI and stroke) were independently associated with elevated Lp(a), especially in patients with MI, young aged and with FH for premature acute vascular ischemic event.
Read more →
Anti-carbamylated protein antibodies in systemic lupus erythematosus patients and its relation to disease activity and severity
Journal ID : AMJ-13-08-2022-10411; Author : Wafaa Soliman, Nagwa Nassar, Neveen Shaker, Dina Farrag,
Abstract : Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease with unknown etiology. Neutrophil extracellular traps play an important role in SLE pathogenesis and may induce the production of autoantibodies against carbamylated proteins (Anti-carP). To measure serum Anti-carP levels in SLE patients and investigate its role in association with disease activity and severity. The study was conducted on 40 SLE female patients and 40 matched healthy controls. All patients were subjected to full history taking and clinical examination. Disease activity was assessed by SLE disease activity index (SLEDAI), Swollen to tender joint ratio (S/T) used to assess joint activity and disease severity was assessed by Katz score. Serum level of Anti-carP was measured using enzyme-linked immunosorbent assay and correlated with disease activity, severity scores, S/T and hand and wrist ultrasonographic findings. Mean age of patients was 33.78±9.1 years (18-50 years), with a mean disease duration of 6.68±6.02 years (0.17-30 years). Anti-carP serum levels, was significantly higher in patients compared to controls (p <0.001). Regarding disease activity, it was significantly higher in active patients compared to inactive ones (p <0.001). Also, it was higher in patients with high disease severity compared to low disease severity (p <0.001). Serum Anti-carP levels showed significant positive correlation with both SLEDAI and KATZ scores (r=0.726, 0.773 and p <0.001 respectively). However, no relation was found between Anti-carP level and clinical or hand wrist ultrasound findings suggestive for arthritis. Serum Anti-carP showed no association with arthritis in SLE patients in this work. However, increased Anti-carP was associated with high disease activity and severity in patients with clinical manifestations other than arthritis. Anti-carP could be a marker of disease activity and severity in SLE.
Read more →
Synthesis and Spectral Identification of Oxazepine Derivatives
Journal ID : AMJ-13-08-2022-10410; Author : Israa Jirjees Neamah, Maitham M. Abdulridha, Bassam A. Hassan,
Abstract : In the presence of ethanol and glacial acetic acids, benzene-1,4-diamine reacted with aromatic aldehydes such as 3-phenylprop-2-enal to generate the imine group known as Schiff bases. Schiff bases IIIA N,N'-(1,4-phenylene)bis(3-phenylprop-2-en-1-imine). treated with anhydride furan-2,5-dione and aromatic anhydride 2-benzofuran-1,3-dione to produced Oxazepine derivatives IVA and IVB respectively. These structures of synthetic oxazepine have been characterized by using FTIR, mass spectral, and elemental analyses. The purity quality of the compounds was done using TLC.
Read more →