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Azerbaijan Medical Journal

(ISSN: 0005-2523)

Azerbaijan medical journal (ISSN: 0005-2523) - is a scopus indexed journal since 1961. The publisher of the journal is Izdatel'stvo Elm by WHO Office in Azerbaijan. Azerbaijan medical journal (AMJ) is also UGC approved. The journal publishes general medicine, health science, psychological, pharmaceutical journals and so on.

Aim and Scope

Azerbaijan Medical Journal

Azerbaijan Medical Journal (ISSN: 0005-2523) - is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to.

Anatomy Physiology Biochemistry Pharmacology Pathology Forensic medicine Microbiology Community Medicine Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases Anaesthesia Cancer research Neurosurgery Orthopedics Gastroenterology Neurology Nephrology Medical education Orthopaedics Paediatrics Reproduction Cardiology Diabetes Surgery Nursing Otolaryngology Dental Psychology Anesthesiology Dermatology Endocrinology Hepatology Urology Venereology Psychiatry Biotechnology Pharmacy ENT Pharmaceutical Chemistry Pharmaceutical Analysis Pharmaceutics Pulmonology Pharmacognosy Pharmaceutical Phatmaceutical Technology Biopharmaceutics Pharmacokinetics Pharmacodynamics Industrial Pharmacy Drug Design Quality Assurance Drug Regulatory Affairs Phytochemistry Drug Delivery Systems Pharmaceutical Nanotechnology Pharmaceutical Microbiology Hospital Pharmacy Clinical Pharmacy Pharmacy Practice Drug Discovery Drug Metabolism Toxicology Clinical Research Pharmacogenomics Phrmacoinformatics Pharmacovigilance< Life Sciences like Chemistry Biomedical Sciences Microbiology Immunology Forensic Epidemiology Oncology Biomedicine Dentistry Physiotherapy Gynaecology Dermatoepidemiology Neuroscience Ophthalmology Sexology Osteology Kinesiology Angiology/Vascular Medicine Critical care Medicine Haematology Infectious Diseases and Vaccinology Bariatrics Pharmacy and Nursing Pharmacognosy and Phytochemistry Radiobiology Clinical immunology Clinical and Hospital Pharmacy Cell Biology Genomics and Proteomics Healthcare Services Healthcare Management Bioinformatics and Biotechnology Geriatric Medicine

Latest Journals

Azerbaijan Medical Journal

Design, synthesis anticytokine storm and molecular docking studies of N-benzyl phenyl isoserine derivatives containing 1,2,3-triazoles
Journal ID : AMJ-30-06-2022-10279; Author : Zahraa sabbar Omran,
Abstract : Cytokine storm is several disorders of immune dysregulation characterized by constitutional symptoms, systemic inflammation, and multiorgan dysfunction that can lead to multiorgan failure if inadequately treated, 1,2,3-Triazoles are one of the most important nitrogen-containing five-membered heterocycles and have a wide range of applications in pharmaceuticals, supramolecular chemistry, organic synthesis, chemical biology and industry. In the current work, the synthesized compounds (1d and 2d) were screened for their anticytokine storm by assay of IL-1b and IL-6 in vivo, confirmations and characterization of the chemical structures related to these compounds were performed using 1H-NMR spectroscopy, FT-IR spectroscopy, and some physicochemical properties such as melting points. Docking study of the final synthesized compounds gave evidence about the affinity of these compounds significantly inhibited IL in comparison to positive groups.
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THE THERAPEUTIC EFFECTS OF MAGNESIUM SUPPLEMENTATION ON GLYCEMIC CONTROL AND LIPID PROFILE IN TYPE II DIABETES
Journal ID : AMJ-27-06-2022-10277; Author : Doaa Khalid, Zeina A. Althanoon, Atallah K. Ibrahim,
Abstract : Individuals with type II diabetes mellitus use dietary supplements on a regular basis. The aim of study was to investigate the therapeutic effect of magnesium supplementation on glycemic control and lipid profile in adult type II diabetes mellitus patients. Seventy type II diabetes patients were allocated into: The intervention group (n=35) was received oral Magnesium oxide 250 mg once daily, and the control group (n=35) was received corn starch as a placebo. The duration of treatment for both groups was two months. After 2 months, the magnesium treated group demonstrated a significant reduction in FSG, HbA1c%, VLDL-C and triglyceride level, while insignificant change in TC, LDL-C and HDL-C, when compared to their pre-supplementation levels and the control group. There is no statistically significant difference between the two studied groups in the mean of age, BMI, systolic and diastolic blood pressure. The intervention group had a significant reduction in FSG (p= 0.034), HbA1c% level was significantly reduced in the magnesium treated group (p = 0.01) while in the control group HbA1c level is increased. Serum triglyceride levels decreased significantly (p < 0.05) in the magnesium supplemented group, but it is increased in the control group (p=0. 54). Oral magnesium supplementation has been shown to be effective in lowering glycaemic control and serum triglyceride level in patients with type 2 diabetes mellitus, and thus may be used as adjuvant therapy for management of patients with type II diabetes mellitus.
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Effectiveness of integrated education and relaxation program on migraine related disability; a Randomised controlled trial
Journal ID : AMJ-27-06-2022-10276; Author : Sara Hisham, Ayat Manzour, Mohammed M. Fouad, Randa M. Amin, Hisham A. Hatata, Diaa Marzouk,
Abstract : Migraine is the most disabling primary headache disorder worldwide. The value of integrative strategies in migraine management has been raised due to the recurrent and provoked nature of migraine. To evaluate the effectiveness of implementing therapeutic patient education and relaxation training program versus usual pharmacological treatment alone on the frequency, severity, and duration of migraine attacks as primary outcome and migraine-related disability and quality of life as secondary outcome. A randomized controlled trial was conducted at the specialized headache clinic of a Tertiary Referral Centre. Sixty patients were randomly assigned to intervention or control groups. Participants in the intervention arm received the education and relaxation training program and were instructed to perform daily relaxation exercises in addition to their routine pharmacological treatment meanwhile the control group only received their routine treatments. Follow-up was done after 1, and 3 months using headache diary and migraine specific quality of life questionnaire (MSQ). After implementation of the program there was a significant reduction in migraine attacks severity in the intervention group compared to the control group, also they had significantly fewer migraine headache days/month and duration of migraine attacks compared to patients in control group. Statistically significant improvement of Role-Function Restrictive, Role-Function Preventive and Emotional Function domains of MSQ. An integrated migraine management program has a significant effect on reducing the burden of migraine attacks and improving the daily activities of migraine sufferers.
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Application of Stress Management on Quality of Life of Diabetes Mellitus Patients at Diabetes Center, Ternate, Indonesia
Journal ID : AMJ-27-06-2022-10274; Author : Amira Bin Seh Abubakar, Muhlisa, Fadila Abdullah,
Abstract : Diabetes mellitus is a progressive disease that can cause various complications, both acute and chronic if not managed properly. resulting in various chronic complications, such as cerebrovascular disease, coronary heart disease, leg vascular disease, eye, kidney and nerve disorders. People with diabetes mellitus have a 2 times greater risk of developing coronary heart disease and cerebral vascular disease, 5 times more likely to suffer from ulcers/gangrene, 7 times more likely to develop terminal renal failure, and 25 times more likely to be blind due to retinal damage than patients. non-diabetic. The purpose of this study was to determine the effect of the application of stress management on the quality of life of people with Diabetes Mellitus in the Diabetes Center, Ternate City. This research was conducted in the working area of the Diabetes Center, Ternate City. The design of this study was a quasi-experimental study, which was a pre and post-test design without a control group. Participants in this study were selected using a technique using simple random sampling with a total sample of 61 people, where the data were analyzed using the t-test statistical test, Anova and correlation. The results of the study found that there was a significant difference between the quality of life of DM sufferers before and after the application of stress management. The patient's quality of life score also increased after stress management was carried out in the form of deep breath relaxation techniques and five-finger hypnosis (p-Value: 0.0005 α: 0.05), while the characteristics of the respondents included gender, marital status, education, family history, and medication do not affect the quality of life.
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Evaluating the clinical significance of Osteoprotegerin Serum Levels as a Predictive Marker in Rheumatoid Arthritis
Journal ID : AMJ-26-06-2022-10273; Author : Ibrahim Majer Mohammed, Adnan Jassim Mohammed Al-Fartosy,
Abstract : Laboratory tests such as the erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and Immunoglobulin M (IgM) have been used as markers of inflammation and disease activity in rheumatoid arthritis (RA), although there is still no clear consensus on when to use one, the other, or all. We aimed to evaluate the level of OPG in RA patients compared with control in order to estimate the predictive value of OPG. Eighty five patients with active RA, attending rheumatology department at Al-Sadder General Hospital in the province of Maysan-Iraq, diagnosed according American College of Rheumatology (ACR) revised criteria were included. The patients' tender and swollen joint counts were calculated. Laboratory investigations were done including ESR by Westergren method, CRP, IgM and OPG by ELISA method, assessment of disease activity using DAS28 score. A non-significant change (p>0.05) was seen in the level of BMI, significantly increased (p<0.01) in levels of ESR, CRP, IgM, and OPG as compared to the control group. All patients showed disease activity at the time of the study, their DAS28 scores ranged from 5.20 to7.40 (Mean ±SD 6.43±0.80). There was a positive and highly significant (p< 0.01) correlation between DAS28 values and ESR, CRP, IgM, and OPG values (r-value was 0.662, 0.695, 0.689, and 0.636, respectively). The OPG was more specific than Rf (IgM, CRP, and ESR) in the diagnosis of RA. So it could be a useful assay in establishing the diagnosis of RA, especially in ambiguous cases or RF negative patients with RA, and also a better predictor of disease severity.
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Chronic pain neuroscience and psychoanalytic theory a narrative review
Journal ID : AMJ-23-06-2022-10272; Author : Leonardo Augusto Medina Ospina,
Abstract : Chronic pain is felt in the body and in the mind. S. Freud, J. Lacan, neurophysiologists, and societies for the study of pain have each explained it to us independently with little success when facing the complexity of this condition by patients and health personnel who care for them, but there are these theories, and you must begin to take them all into account to understand pain in its entirety. This review aims to describe the concept of chronic pain in a simple way and as an appetizer through, on the one hand, psychoanalytic theory and, on the other, neuroscience. In no way is it intended to equate psychoanalytic knowledge with neurobiological knowledge since their sources and scientific method are different. If similarities are found between both ways of understanding chronic pain, they should be understood as the author's opinions or the reader's deductions. What is desired here is to sow curiosity about the subject and in the future if it is possible to integrate the two ways of understanding long-term pain. For this narrative review, a manual and automated literature search was carried out in biomedical databases, disciplines related to neuroscience, psychoanalysis, and mental health, using search terms according to Medical Subject Headings. Textbooks on the topics and representative authors of psychoanalytic theory and neuroscience were also consulted. Although there are psychoanalytic and neurobiological approaches in the study of chronic pain, they all understand it independently, and their integration has not been achieved so far. However, we can get to know the bases of each aspect to venture into this company in the future. There is a need to increase research on chronic pain conditions, which correlates neurobiological and psychoanalytic aspects that contribute to achieving a multidimensional and effective treatment. It is especially urgent to find a way to "measure" psychoanalytic concepts to confirm them in the light of current scientific method.
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EVALUATION OF GLYCEMIC CONTROL IN USERS OF ORAL CONTRCEPTIVE PILLS IN MOSUL CITY
Journal ID : AMJ-22-06-2022-10271; Author : Farah R.Noori, Zeina A.Althanoon,
Abstract : Family planning are increasingly challenging due to combined oral contraceptive (COC) pills associated side effects, including metabolic derangement. We aimed to identify the glycemic side effect of COC on blood sugard and HbA1c. Women planning to take COC pills enrolled in the present study. Blood samples withdrawn and partially used for HbA1c measurement and serum samples separated from left fraction of the blood and used for measurement of random blood sugar (RBS). The results confirmed that no differences reported regarding RBS while HbA1c shown variation in age- and weight-dependent manner. To sum-up, continuous use of COC will be associated with alteration in metabolic status indicated by elevated HbA1c. We do advice patients to change their lifestyle via increasing physical activity and reduce high-calories diet.
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Factors contributed to dehiscent uterine scar in women with previous one cesarean section
Journal ID : AMJ-21-06-2022-10270; Author : Areej Kazim Shareef Kareem, Zahraa Muhmmed Jameel Al-Sattam, Samar Dawood Sarsam, Zaid Al-Attar,
Abstract : A caesarean section is often done when vaginal birth might jeopardize the baby's or mother's life or health, however it has been performed on request in recent years. The rate has grown to at least 25%. One of the serious complications after cesarean section is development of uterine dehiscent scar. To assess the possible causes of dehiscent scar in pregnant ladies with previous one cesarean section. Observational cross-sectional prospective study, carried out from the beginning of January 2020 to December 2020, at Elwiya Maternity Teaching Hospital - Baghdad. Two hundred fifty patients were enrolled in the study, full history was taken regarding their previous scar, and they were fully assessed regarding current pregnancy and all patients were followed up during cesarean section and afterwards. The rate of dehiscent scar was (12%). It is found that the rate was significantly inversely related to the time space between pregnancies; higher incidence of dehiscent scar in those women whose interpregnancy interval was 6 months or less while the lowest incidence in those whose interpregnancy interval was ≥ 12 months. Significant relationship has been found with the type of hospital, as women whose previous cesarean section was performed at the general hospitals were less likely to have dehiscent scar than those at private hospital, with gestational age of ≤ 36 completed weeks in both the previous and the current cesarean section and with the trial of labor before performing cesarean section. Failure of progress is an important risk factor associated with uterine scar dehiscence. Cesarean sections performed at or before 36 completed weeks gestation in the previous pregnancy were associated with higher rate of uterine scar dehiscence in the current pregnancy. Previous cesarean sections performed in private hospitals were associated with higher rate of uterine scar dehiscence in the current pregnancy.
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Study of the Predictive factors for conversion of Laparoscopic Cholecystectomy to Open Cholecystectomy
Journal ID : AMJ-21-06-2022-10269; Author : Dr.Haider Kamel Hussein, Dr.Nagham Zuhair Abdulkareem, Dr.Abdulrahman Mahmood Mohammed,
Abstract : Laparoscopic cholecystectomy has become the standard treatment for symptoms of gallbladder disease. However, there are still a significant proportion of patients for whom laparoscopic cholecystectomy cannot be performed successfully and who need to switch to open surgery. In this prospective study, we reviewed (140) patients undergoing laparoscopic cholecystectomy during the last three years (January 1st, 2019 to January 1st, 2020) at Al-Kadhimiya teaching hospital and recorded reasons for conversion to OC. Statistical analysis was then performed to identify factors predictive of increased risk for conversion. Our unit’s practice on timing for cholecystectomy general practices interval cholecystectomy for most of our patients. Patients who underwent emergency cholecystectomy were excluded from this study. About 20% of cases that were performed during the first one and half year of the study were converted, so about 3.3% of converted cases were in patients with BMI over 30, as well as 18.8% of cases in patients in which identification of calot's triangle lasted more than 30 minutes were converted, 20% of cases that were performed during the first one and half year of the study were converted. Patients with a high predicted risk of conversion could be operated on either by or under the supervision of a more experienced surgeon. Surgeons in the early phase of their training could operate on patients with low risk of conversion, especially if they are not operating under the supervision of an experienced laparoscopic surgeon. Also, a high predicted risk of conversion may allow the surgeon to take an early decision to convert to OC when difficulty is encountered during dissection; this may shorten the duration of surgery and decrease the associated morbidity.
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The Impact of Vitamin D Deficiency on Some Immunomodulatory Markers in Pregnant Women with Threatened Abortion
Journal ID : AMJ-21-06-2022-10268; Author : Rafal Jalil Al-Saigh, Enass Najem Oubaid, Nada Khazal Kadhim Hindi, Ahmed H Al-Humadi, Hussam Wahab Al-Humadi,
Abstract : The protective mechanism of vitamin D (VD) on the immune system played an important role behind many health problems including abortion. Our aim was to investigate the levels of VD and some immunomodulatory markers (IL-6, TNF-α and INF-γ) in pregnant women with threatened abortion (TA) and their effects on their obstetric health. This study including 132 pregnant participants with TA visiting maternity hospital in Babel province, Iraq. The demographic data including previous and current obstetrical history and body mass index were collected by well-trained researcher following structured questionnaire after obtaining their verbal consent. Laboratory Investigations were done with estimation of VD, IL-6, TNF-α and INF-γ. The mean level of VD was 19.83±43.59 ng/ml while the mean levels of IL-6: 389.45±70.88, TNF-α: 118.78±44.11 and INF-γ: 100.39±20.13 pg/ml with related percentage among participants for low VD was 84%, high IL-6 was 66%, high TNF-α was in 43% but only 23% had high INF-γ in relation with normal values. The frequency of abortion was significantly increased with low VD and high IL-6 (p<0.05) with high correlation between them (r2=0.89). High incidence of TA associated with low level of VD accompanied with high serum levels of IL-6. This adverse pregnancy outcome may be associated with some form of autoimmune diseases with evidence that hypovitaminosis D was correlated with high proinflammatory markers (IL-6, TNF- α and IFN- γ) and worse form of TA and the role of VD is to correct these pro-inflammatory markers.
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