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Volume - 63 , Issue 04
05 Apr 2023

Azerbaijan Medical Journal

(ISSN: 0005-2523)

Azerbaijan medical journal (ISSN: 0005-2523) - is a scopus indexed journal since 1961. The publisher of the journal is Izdatel'stvo Elm by WHO Office in Azerbaijan. Azerbaijan medical journal (AMJ) is also UGC approved. The journal publishes general medicine, health science, psychological, pharmaceutical journals and so on. Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Interventional Pulmonology Zhenkong Kexue yu Jishu Xuebao/Journal of Vacuum Science and Technology

Aim and Scope

Azerbaijan Medical Journal

Azerbaijan Medical Journal (ISSN: 0005-2523) - is a peer-reviewed journal. The journal seeks to publish original research articles that are hypothetical and theoretical in its nature and that provide exploratory insights in the following fields but not limited to. Zhongguo Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of China University of Petroleum (Edition of Natural Science) Tobacco Science and Technology Teikyo Medical Journal Connected Health Wuhan Ligong Daxue Xuebao (Jiaotong Kexue Yu Gongcheng Ban)/Journal of Wuhan University of Technology (Transportation Science and Engineering) Zhonghua yi shi za zhi (Beijing, China : 1980) Agricultural Mechanization in Asia, Africa and Latin America International Medical Journal Technology Reports of Kansai University Asia Life Sciences Open Access Journals Tagliche Praxis

Anatomy Physiology Biochemistry Pharmacology Pathology Forensic medicine Microbiology Community Medicine Otorhinolaryngology Internal Medicine General Surgery Obstetrics and Gynecology Radiology Pulmonary Medicine Dermatology and Venereal diseases Infectious Diseases Anaesthesia Cancer research Neurosurgery Orthopedics Gastroenterology Neurology Nephrology Medical education Orthopaedics Paediatrics Reproduction Cardiology Diabetes Surgery Nursing Otolaryngology Dental Psychology Anesthesiology Dermatology Endocrinology Hepatology Urology Venereology Psychiatry Biotechnology Pharmacy ENT Pharmaceutical Chemistry Pharmaceutical Analysis Pharmaceutics Pulmonology Pharmacognosy Pharmaceutical Phatmaceutical Technology Biopharmaceutics Pharmacokinetics Pharmacodynamics Industrial Pharmacy Drug Design Quality Assurance Drug Regulatory Affairs Phytochemistry Drug Delivery Systems Pharmaceutical Nanotechnology Pharmaceutical Microbiology Hospital Pharmacy Clinical Pharmacy Pharmacy Practice Drug Discovery Drug Metabolism Toxicology Clinical Research Pharmacogenomics Phrmacoinformatics Pharmacovigilance< Life Sciences like Chemistry Biomedical Sciences Microbiology Immunology Forensic Epidemiology Oncology Biomedicine Dentistry Physiotherapy Gynaecology Dermatoepidemiology Neuroscience Ophthalmology Sexology Osteology Kinesiology Angiology/Vascular Medicine Critical care Medicine Haematology Infectious Diseases and Vaccinology Bariatrics Pharmacy and Nursing Pharmacognosy and Phytochemistry Radiobiology Clinical immunology Clinical and Hospital Pharmacy Cell Biology Genomics and Proteomics Healthcare Services Healthcare Management Bioinformatics and Biotechnology Geriatric Medicine Bulletin of National Institute of Health Sciences Journal of the Austrian Society of Agricultural Economics Gongcheng Kexue Yu Jishu/Advanced Engineering Science Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery Interventional Pulmonology Zhenkong Kexue yu Jishu Xuebao/Journal of Vacuum Science and Technology Wuhan Ligong Daxue Xuebao (Jiaotong Kexue Yu Gongcheng Ban)/Journal of Wuhan University of Technology (Transportation Science and Engineering) Zhonghua yi shi za zhi (Beijing, China : 1980) Zhongguo Shiyou Daxue Xuebao (Ziran Kexue Ban)/Journal of China University of Petroleum (Edition of Natural Science) Tobacco Science and Technology Teikyo Medical Journal Connected Health

Latest Journals

Azerbaijan Medical Journal

Agricultural Mechanization in Asia, Africa and Latin America International Medical Journal Technology Reports of Kansai University Asia Life Sciences Open Access Journals Tagliche Praxis Bulletin of National Institute of Health Sciences Journal of the Austrian Society of Agricultural Economics
Insulin Resistance and Residual ß-Cell Function Among Persons with Impaired Fasting Glycaemia
Journal ID : AMJ-17-09-2022-10553; Author : Hasnaa Yagoub Yousif, Salman K. Ajlan,
Abstract : Impaired fasting glycaemia (IFG) is a condition, in which a person's fasting blood glucose levels are consistently higher than the normal range, but below the diagnostic cut-off for diabetes mellitus (DM). ß-cell dysfunction and insulin resistance (IR) have a principal role in the pathogenesis of IFG. Patients with IFG are at high risk of progression to diabetes, and developing atherosclerotic cardiovascular disease (ASCVD), The present study was designed, to determine the degree of IR (HOMA-IR) and ß-cell dysfunction (HOMA-B) among patients with IFG, and also to correlate HOMA-IR and HOMA-B with biochemical and anthropometric variables. The study included 143 patients with IFG, 61 males and 82 females, 14 – 70 years of age, and 150 apparently healthy subjects, 62 males and 88 females, 15-70 years age as a control group. Physiological measurements include weight, height, waist circumference (WC), and blood pressure (BP). Biochemical measurements include fasting blood glucose (FBG), glycated haemoglobin (HbA1c), insulin, total cholesterol (TC), triglycerides (TG), high-density lipoprotein-cholesterol (HDL-C) and low-density lipoprotein-cholesterol (LDL-C). In addition, HOMA-IR and HOMA-B were also determined. Insulin level was significantly higher among patients with IFG in comparison to control subjects, (P < 0.000). There were no significant differences in FBG and HbA1c between IFG and control group, (P > 0.05). Concerning HOMA-IR and HOMA-B, patients with IFG showed a significantly higher HOMA-IR and a significantly lower HOMA-B values compared to control subjects, (P = 0.000). LDL-C was significantly higher among patients with IFG in comparison to control subjects, (P < 0.05). There were no significant differences in TC, TG and HDL-C between the two groups, (P > 0.05). Correlation analysis in patients with IFG revealed a positive correlation of HOMA-B with insulin, (P < 0.01) and a significant negative correlation with LDL-C, (P < 0.01). While, HOMA-IR showed a significant positive correlation with insulin, (P < 0.01), FBG (P < 0.01) and TG (P < 0.05). We concluded that patients with IFG have significantly higher insulin and HOMA-IR and significantly lower HOMA-B values compared with control subjects. This indicates that these patients are a high risk of progressing to T2D and its complications. In addition, the significantly higher LDL-C among patients with IFG in comparison to control persons may increases the risk of macro-vascular ASCVD.
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Age, Gender, and ABO Blood Group Relation to Immunological Parameters in Children Infected with E. histolytica
Journal ID : AMJ-17-09-2022-10552; Author : Hardi Sidiq Mohammed, Latif Omer Mohammed, Shahnaz Abdul Kader Ali, Heshu Sulaiman Rahman,
Abstract : Amoebiasis is an enteric protozoan disease of the human gastrointestinal tract caused by E. histolytica, which is a public health problem in many developing countries. Especially in poor sanitation areas. The study aimed to estimate some immunological parameters in symptomatic amoebic children. The study was conducted in the Pediatric Teaching Hospital in Sulaymaniyah province during September - December 2021. The serum was taken from 80 amoebic infected children (patient group) and 80 parasite-free children (control group) for estimating IL-17, IFN- γ, and TNF-α levels by applying the ELISA technique and for CRP estimation using Cobas-C311. A highly significant difference was recorded in the serum concentration of CRP between the patient group and the control group (P<0.001). The serum concentration of IL-17 was not significantly different between the two studied groups (P>0.05); however, IFN-γ level was reported to be significantly different (P≤0.05), and TNF-α serum level noted a highly significant difference (P<0.001). The highest level of IL-17 was recorded in infected males compared to the females, with a significant difference. Regarding age and blood group, no significant difference was recorded in infected children. The immunological measurement of CRP and TNF-α revealed a highly significant difference in the patients compared to the controls, and the serum level of IFN-γ documented significant differences. Also, significant differences were recorded in serum IL-17 among infected children of different ages.
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Adherence to Antidiabetic Medication and its Related Factors in Type Two Diabetes Mellitus Patients, Sulaimaniyah City, Iraq
Journal ID : AMJ-17-09-2022-10551; Author : Derin Ahmed Khdir, Mohammed Omer Mohammed,
Abstract : Type 2 diabetes mellitus (T2DM) implies the highest incidence of diabetic cases. T2DM is related to metabolic ailments in the pancreas, kidneys, liver, and intestines. To determine the impact of adherence to antidiabetic medication (ADMs) on glycemic control in T2DM patients. This cross-sectional study enrolled 245 participants (119 intervention patients and 126 non-intervention patients) with T2DM in Diabetes and Endocrine Center, Sulaimaniyah, Iraq, from January to August 2021 through direct interviews using a special self-created questionnaire. Information leaflets and medication counselling were provided to the intervention group by the researcher. ADMs was evaluated using the Morisky Medication Adherence Scale item 8 (MMAS-8). Also, fasting blood glucose (FBG) and glycosylated hemoglobin (HbA1c%) were checked to assess glycemic control among the participants. The counselling program improved ADMs potentially as the rate of medium adherence increased significantly from 5.0% to 31.9% (p<0.001), with a significant perfection in glycemic control in the intervention group from 13.9% (before the intervention) to 21.8% (after the intervention) (p=0.039). However, there was no significant difference between ADMs and glycemic control (p>0.999). Patients’ education and medication counselling significantly improved ADMs and glycemic control in people with T2DM.
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Illness Beliefs and Its Relationship with Diabetes Self-Care Practice in Patients with Type 2 Diabetes Mellitus in Indonesia
Journal ID : AMJ-17-09-2022-10550; Author : Made Sumarwati, Yunita Sari,
Abstract : Diabetic patients in Indonesia have poor self-care practices. Illness belief might affect diabetes self-care practice in Indonesia. However, up to date, the illness belief of Indonesian diabetic patients toward self-care is still unclear, and whether illness belief and its domains are the predictors of diabetes self-care practice in Indonesia is still unknown. Therefore, this study aimed to assess the illness belief and to assess whether illness belief and its domains are the predictors of diabetes self-care in the Indonesian context. A cross-sectional study was conducted on 625 T2DM patients from public health centers in Purwokerto City, Indonesia. A Brief Illness Perception Questionnaire (BIPQ) and Summary Diabetes Self-Care activities (SDSCA) were used to assess illness beliefs and diabetes self-care behaviors respectively. A hierarchical multiple regression analysis was conducted to identify the predictors of diabetes self-care behaviors. The scores of IBPQ domains (i.e., consequences, timeline, personal control, treatment control, identity, concern, understanding, and emotional response) were 5.00 ± 2.65, 4.84 ± 2.59, 6.16 ± 1.92, 7.21 ± 1.97, 5.00 ± 2.07, 4.91 ± 2.61, 5.31 ± 2.01, and 4.64 ± 2.51, respectively. The regression analysis showed the predictors of diabetes self-care behaviors to be consequences (p< .05), personal controls (p< .05), and duration of DM (p< .05). This study provides evidence that two domains of illness beliefs are predictors of diabetes self-care behaviors in Indonesia. The domains are consequences and personal control. There is a need to design educational programs focusing on illness beliefs to improve diabetes self-care behaviors in Indonesia.
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Effect of ZrO2 nanoparticles on liver tissue of infected mice of visceral leishmaniasis
Journal ID : AMJ-17-09-2022-10548; Author : Mohammed H. Mohammed, Hadeel A. Majeed, Nadheer J. Mohammed,
Abstract : Visceral leishmaniasis consider a great health problem in Iraq, the traditional antileishmanial therapies are toxic and most are costly. For this reason, new approaches in the treatment of leishmaniasis are requested, zirconia nanoparticles ZrO2NPs, is a nano-sized and hollow colloidal metal oxide, it was recorded as anticancer agent, the approach was to prepare 17.4 μg/ml of ZrO2NPs by pulsed laser ablation. These nanoparticles are described to confirm the shape, size and other physical properties of the crystal using the following techniques: X-Ray Diffraction (XRD), results were indicated diffraction peaks at (28.2°, 31.5°, 38.5°, 50°, and 59.8°) were correspond to the (111, 111, 120,022 and 131), respectively. The Transmission Electron Microscopy (TEM) shown confirms the formation of nanostructures with granular size by 50 pulses of laser. The histological study included preparation of cross-sections of liver tissue of infected mice and dosed with ZrO2NPs, the results exhibited mild central venous congestion and mild sinusoidal dilation after 7th day of administration and normal appearance with a few infiltration of hepatocytes and small necrosis, hydropic degeneration after 21th day compared with control positive group which exhibited moderate central venous congestion, mild infiltration and the magnified sections revealed moderate cellular swelling and necrosis of hepatocytes after 7th day and became sever damage with multiple focal necrosis, sinusoidal dilation, and infiltration of inflammatory cells with disarrangement of hepatic cords and increased kupffer cell after 21th.
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SOME IMMUNE ASPECTS IN PATIENTS WITH CUTANEOUS LEISHMANIASIS IN AL-KIFIL DISTRICT/BABYLON PROVINCE
Journal ID : AMJ-17-09-2022-10546; Author : Aseel Zuhair Sherba, Salah Yousif Mohsin, Rana Talib Naser, Haitham M.H.Al-Awadi, Qayssar Joudah Fadheel,
Abstract : The study was performed to evaluate the Epidemiological status of cutaneous leishmaniasis in the Al-Kifil district /Babylon province during the period 1/9/2017 to 1/3/2018, 106 cases visited the Al-kifil general hospital and some private clinics in this district were studied. The infestation was diagnosed by dermatologist physician, The study was performed to evaluate the Epidemiological status of cutaneous leishmaniasis and evaluation some hematological parameter changes of infected persons with cutaneous leishmaniasis in the Al-Kifil city /Babylon governorate during the period 1/9/2017 to 1/3/2018 500 cases visited the Al-kifil general hospital and some private clinics in this city were studied. The infection was diagnosed by dermatologist physician, all similar cases to cutaneous leishmaniasis were excluded. 106 positive case with cutaneous leishmaniasis were examined from patient with the disease referring to Al-kifil general hospital and private clinics. The study revealed that the percentage of infection with cutaneous leishmaniasis was 21%. The percentage of infection with the CL was 40% with the age 1-14 year and 10% with age 15-40. Male were more infected with the disease (65%) than female (35%). Rural area were more epidemic with this disease (55%) in comparing with area near Al-kifel city (25%) and inside Al-kifil city (20%) respectively. Arms and legs were more exposed to infection (60%) with ulcer than head (40%). Multiple ulcer represent more prevalence in the body (60%) comparing with the single (40%). Wet ulcer were more prevalent in incidence of infection (83%) in the Al-kifil community in comparing with dry ulcer (17%). Venous blood was drawn patient with cutaneous leishmaniasis for determination of some blood parameter (hemoglobin, pact cell volume, platelet, white blood cells, eosinophil cells, lymphocytes, neutrophil cells, and neutrophil/ lymphocyte ratio) and IgM, IgG, and IgA. The mean level of Hb and PCV was significantly decrease in patient with cutaneous leishmaniasis (Hb=12.05), (PCV=23.68) in comparison with the control group, while there was an increase in (platelet=269000, WBC=6500, eosinophil=0.26 k/l, lymphocyte=0.35 k/l, neutrophil=5.71 k/l, and neutrophil/lymphocyte ratio=2.23). The result also revealed a significant decrease in (IgG,=0.3 g/l, IgM=0.25 g/l) respectively but no change in IgA value was notice.
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Anatomical and Histological changes of anal canal in patients with fistula in ano: A Study in Mosul
Journal ID : AMJ-17-09-2022-10545; Author : Omar Al-Jalili, Muna AlHamdany, Mohammed Hayawi, Taha AlSaig,
Abstract : Anal fistula is a common harmful and irritating anorectal condition. It is a chronic abnormal narrow tunnel communicating between the epithelial surface of the anal canal and the perianal skin. This study aimed to determine the anatomical and histological findings of the resected fistulous tract following fistulectomy in Mosul city. Fifty fistulectomy specimens following fistulectomy operation were collected from the Department of General Surgery in Al-Salaam Teaching Hospital. The work was conducted in the Department of Anatomy, College of Medicine, University of Mosul. The included cases are both adult male and female in the age group of 15-60 years. The biopsies will be fixed for more than 24 hour in 10% neutral buffered formalin then tissue processing, sectioning as well as staining with hematoxylin and eosin for histological analysis. Half (50%) of patients were in the age group between thirty and forty years and male were predominantly affected more than female. Chronic nonspecific inflammation with neutrophils infiltration was the predominant histological finding. Foreign body type of giant cells lining the fistulous tract was observed in 6% of cases, the fistulous tract was surrounded by non caseating granuloma in 12% while 10% of cases showed fistulous tract lined by stratified squamous epithelium surrounded by granulation tissue. The blood vessels appeared congested and dilated in 10% of cases while inflammatory cells infiltration and interstitial hemorrhage were observed in 6% of patients. Fistula in ano affects male than female with more incidence in the middle aged individuals, histopathological evaluation is obligatory to determine the underlying pathogenesis and the plan of management.
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THE EFFECT OF HEALTH EDUCATION AND THERAPEUTIC GROUP THERAPY TO PREVENT SMARTPHONE ADDICTION IN SCHOOL-AGE CHILDREN
Journal ID : AMJ-17-09-2022-10544; Author : Reza Fajar Amalia, Achir Yani S. Hamid, Ice Yulia Wardani,
Abstract : One of the products of telecommunication technology development is the smartphone. Smartphone using during the Covid-19 pandemic was increased not only in adult users but also in school-age users. Higher user's smartphone in school-age children at risk of causing the addiction. Smartphone addiction does not only cause physical problems but also social, behavioral, and affective aspects. Smartphone addiction can cause depression, neuroticism, and obsessive-compulsive behavior disorders and affect academic achievement. This study is aimed to determine the effect of health education and therapeutic group therapy to prevent smartphone addiction in school-age children. A quasi-experimental research pre-post test with a control group design was used. A total of 69 children were divided into 2 groups. Group intervention 1 consisted of 34 children receiving health education and therapeutic group therapy, assigned to 7 subgroups, whereas group intervention 2 consisted of 35 children receiving only health education and assigned to 7 subgroups. Respondent characteristic data were analyzed using descriptive statistics. The homogeneity of the two groups was tested using Chi-square, a test of the normality of the data using Kolmogorov Smirnov test and data normally distributed, the bivariate analysis using repeated ANOVA. This study found that the decrease in smartphone addiction was greater and significant in the group who received health education and therapeutic group therapy (p-value <0.05). Health education combined with therapeutic group therapy was recommended as an effective nursing intervention to prevent smartphone addiction in school-age children.
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Adsorption of Hormones FSH and LH on the Chitosan-Graphene Oxide -Molybdenum Oxide Nanocomposites
Journal ID : AMJ-16-09-2022-10543; Author : Assel A. Hadi, Hussein K. Al-Hakeim, Nada Y. Fairooz,
Abstract : Molybdenum oxides nanomaterials are gaining mounting popularity with potential applications in various fields due to their unique physicochemical properties. Making a nanocomposite is amended the properties of the original nanoparticles (NPs). In the present study, molybdenum dioxide/Graphene oxide /Chitosan nanocomposites (CS/GO-MoO2-NPs) were prepared using a chemical method and used for the extraction of precious proteins from human serum. CS/GO-MoO2-NPs were used as a surface to extract follicular-stimulating hormones (FSH) and luteinizing hormone (LH) from the human serum. The newly synthesized nanocomposite was characterized using routinely used techniques, including SEM, FTIR, and XRD measurements. Different concentrations of the hormone solutions were incubated with a fixed amount of NPs, and quantities of hormone absorbed were calculated. The studies were carried out at different temperatures to calculate the thermodynamic parameters. Furthermore, the composites were incubated with the human serum to extract the FSH and LH hormones and eluted the desorbed hormone. The results revealed the formation of stable slabs of CS/GO-MoO2-NPs with an average size of 23.5 nm. The nanocomposite can adsorb significant amounts of the FSH and LH hormones (7.07ug/g) from human serum. Freundlich's adsorption isotherm was obeyed during the adsorption process, showing that the nanocomposite surface was heterogeneous. Exothermic and spontaneous adsorption processes were revealed by thermodynamic research. FSH and LH hormones can be adsorbed spontaneously on the surface of CS/GO-MoO2-NPs as a tool for extracting hormones from serum and as a supporting media for FSH and LH in analytical kits such as ELISA and protein microarrays.
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Separation of Follicular - Stimulating Hormone from Serum by Chitosan-Graphene Oxide-Selenium Oxide Nanocomposites
Journal ID : AMJ-16-09-2022-10542; Author : Assel A Hadi, Nada Y Fairooz, Hussein K Al-Hakeim,
Abstract : Selenium oxide nanoparticles (SeO2-NPs) have gotten much attention because of their favourable in addition to unique bioactivities. The use of nanocomposites for the extraction of precious proteins is an important field of study. The present work has introduced a new technique for synthesizing selenium oxide nanoparticles (SeO2-NPs) coated with chitosan and graphene oxide nanocomposites (CS/GO-SeO2-NPs). CS/GO-SeO2-NPs were used as a surface to extract follicular-stimulating hormone (FSH) from the human serum. The newly synthesized nanocomposite was characterized using routine techniques, including scanning electron microscopy (SEM), Fourier transition infrared spectrum (FTIR), and X-ray diffractometer (XRD) measurements. Different concentrations of the hormone solutions were with incubation a fixed the amount of NPs and the amount of hormone absorbed was computed using these numbers. To calculate the thermodynamic parameters, the experiments were carried out at various temperatures. Furthermore, the composites were incubated with the human serum to extract the FSH hormone and eluted the desorbed hormone. The results reveal the presence of stable flakes of CS/GO-SeO2-NPs with a 14.7 nm average size. The nanocomposite can adsorb significant amounts of the FSH hormone (7.07ug/g) from human serum. Freundlich's adsorption isotherm was followed during the adsorption phase, showing that the nanocomposite surface was heterogeneous. Exothermic and spontaneous adsorption processes were revealed by thermodynamic research. FSH hormone can be adsorbed on the surface of CS/GO-SeO2-NPs spontaneously as a tool for extracting hormones from serum and as a supporting media for FSH in the analytical kits.
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