Minimum Service Standard (MSS) for health is a reference for Regional Government to provide Health Services that every citizen deserves to receive minimally. This study aimed to analyze the implementation of Minimum Service Standard for pregnant women's health service in South Konawe Regency. The research design used a case study method with a qualitative-explorative approach through observation, in-depth interviews and literature studies of all research informants that selected by purposive sampling. The variables of this study used the theory of policy implementation by Edward III (1980) including: communication, resources, disposition and bureaucratic structure. The results of this study indicate that communication has not run optimally, information is not clear and detailed. The elements of transmission and consistency are good, but the element of clarity is not running optimally. Resources are still inadequate, human resources are available as needed, but Human Resource capabilities are still not optimal, budget is still limited, and there are still problems that related to support health facilities. Disposition has been going pretty well. commitment and implementation support are quite good, it has carried out coordination and commitment that involve cross-program and related cross-sectors. The bureaucratic structure is already running quite well. The implementation of Minimum Service Standard for pregnant women's health services in South Konawe Regency has is already running quite well. It is hoped that the health office, Public Health Center, local government of South Konawe Regency will improve aspects of communication, resources, disposition and bureaucratic structure in their implementation.