The study aims to assess the effectiveness of Brief Cognitive Behavioral Therapy (BCBT) treatment on methamphetamine users on the severity of dependency on methamphetamines and to determine the intensity of desire for methamphetamines in a sample of Semarang prison inmates of Indonesia. This study applied a quantitative research method with a quasi-experimental design. The experimental group received BCBT treatment for 4 sessions, while the control group received health education for 4 sessions. All data were analyzed using Mann-Whitney and Wilcoxon by IBM SPSS seri 26.0 for windows. The results of the final treatment, when viewed from the post-test using the SDS (Severity of Dependence Scale) and Brief Craving scale, showed a decrease in craving in the experimental group and no change in dependence, but in the control group, there was an increase in feelings of addiction and dependence on methamphetamine. BCBT was successful in helping PWUD stop using methamphetamine. They understood that busy activities carried out in daily activities could help become a diversion if the feeling of wanting to use methamphetamine arose. In addition, subjects who have received sessions from the counselor commit themselves to no longer using shabu.