Abstract :
Vulvovaginal candidiasis (VVC) is an infection of the lower female reproductive tract mucosa caused by the polymorphic opportunistic fungus Candida albicans. Colonization of C. Albicans in the vaginal lumen is generally asymptomatic. Vulvovaginal candidiasis (VVC) is a common infection of the genital tract that affects millions of women worldwide. This study aims to determine the effect of methanol extract of Bajakah (Spatholobus littoralis hassk) on the morphology of Candida albicans in the vagina of female rats (Rattus norvegicus) Vulvovaginal Candidiasis model. This study used a quantitative approach, namely a simple experimental design (actual trial) with a completely randomized design method, and the posttest-only control group design approach was chosen. Examination of the hyphae of the fungus Candida albicans was carried out using a qualitative descriptive design approach, which describes, describes, and describes the object under study. The results showed that there was an increase in serum levels of IL-10 in the blood of KVV model rats by administration of pirated extract in each treatment group (P1, P2, and P3) which showed the mean respectively: P1 136.609 pg/mL, P2 147.212 pg/ mL, and P3 148.270 pg/mL with a p-value of 0.021 and this study also showed that there was an effect of giving piracy extract in various concentrations on serum IL-10 levels, that is, the more concentrations used, the serum IL-10 levels increased. Administration of various doses of methanol extract of Bajakah (Spatholobus littoralis hassk) did not affect the decrease in the morphology of Candida albicans in the vagina of female rats (Rattus norvegicus) Vulvovaginal Candidiasis (KVV) model, in this case, the number of hyphae microscopically did not increase or decrease with increasing concentration of the extract.