Temporary hemodialysis catheter (NTHC, Non-tunneled hemodialysis catheter) can be used in cases of Acute Kidney Injury (AKI) and Chronic Kidney Disease (CKD) in emergency settings. According to KDOQI 2019 guidelines, NTHC should not exceed two weeks in Internal Jugular or Subclavian vein and five days in the femoral vein. However, the use of NTHC in Indonesia and many other countries exceed the recommended use. This study aims to determine the durability of NTHC on three different sites (Internal Jugular, Subclavian, and Femoral Vein) and determine factors influencing the durability of NTHC. This prospective cohort observational analytic study used a consecutive sampling method to recruit subjects that meet inclusion and exclusion criteria. Every subject was then followed until the occurrence of an event. Data censoring was applied for the elective removal of the NTHC. Of the 74 subjects, the durability NTHC in Internal Jugular, Subclavian and Femoral veins were 36.29, 46.91, and 33.00 days respectively. By statistics, no significant differences were observed. However, multivariate analysis showed that the risk of the event was four times higher in the femoral vein site. The most extended catheter durability was the subclavian vein, with the femoral vein showing the highest risk.